103753-78-2

Basic information

• Product Name: 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE
• Synonyms: 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE;3-(3,4-dichlorophenyl)dihydrofuran-2(3H)-one;2(3H)-Furanone, 3-(3,4-dichlorophenyl)dihydro-
• CAS NO: 103753-78-2
• Molecular Formula: C₁₀H₈Cl₂O₂
• Molecular Weight: 231.08
• Mol File: 103753-78-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 384.8 °C at 760 mmHg
• Flash Point: 173 °C
• Appearance: /
• Density: 1.406 g/cm³
• Vapor Pressure: 3.97E-06mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE(103753-78-2)
• EPA Substance Registry System: 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE(103753-78-2)

Safety Data

• Hazardous Substances Data: 103753-78-2(Hazardous Substances Data)

Usage

Description

3-(3,4-Dichloro-phenyl)-dihydro-furan-2-one is a synthetic chemical compound with the molecular formula C10H6Cl2O2. It is a white crystalline solid characterized by a melting point of 68-70°C and a boiling point of 317-318°C. 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE is soluble in organic solvents such as acetone, chloroform, and ether, and is recognized for its potential as a fungicide and its use as a building block in the synthesis of various biological and pharmaceutical derivatives.

Uses

Used in Pharmaceutical Industry:
3-(3,4-Dichloro-phenyl)-dihydro-furan-2-one is used as an intermediate in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs. Its unique chemical structure allows it to be a versatile building block in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical industry, 3-(3,4-Dichloro-phenyl)-dihydro-furan-2-one is used as a potential fungicide. Its antimicrobial properties have been the subject of research for applications in protecting crops from fungal infections, thereby enhancing agricultural productivity.
Used in Specialty Chemicals Production:
3-(3,4-Dichloro-phenyl)-dihydro-furan-2-one also serves as a key component in the production of specialty chemicals. Its chemical properties make it suitable for various industrial applications where specific chemical interactions are required.

InChI:InChI=1/C10H8Cl2O2/c11-8-2-1-6(5-9(8)12)7-3-4-14-10(7)13/h1-2,5,7H,3-4H2

Upstream product

• 17739-45-6 2-(2-bromoethoxy)tetrahydropyran 
• 6725-44-6 methyl 2-(3,4-dichlorophenyl)acetate 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 213380-60-0 cyanoalcohol 
• 40878-09-9 diethyl 2-(3,4-dichlorobenzylidene)malonate 
• 40878-08-8 cyanoester 

Downstream Products

• 184969-75-3 alpha-(2-bromoethyl)-3,4-dichlorophenylacetic acid 
• 1131739-29-1 3-(3,4-dichloro-phenyl)-3-fluoro-dihydro-furan-2-one 
• 1093078-83-1 3-(3,4-dichloro-phenyl)-3-methyl-dihydro-furan-2-one 
• 213380-62-2 selenide 

Relevant articles and documents

PIPERIDINE DERIVATIVES AS NK3 ANTAGONISTS

The invention relates to a compound of formula wherein Ar1, Ar2, R1, R2, R3, R4, R5, and R5′ or to a pharmaceutically active salt thereof. The compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).

A convenient synthesis of 3-arylbutanolides and 3-arylbutenolides

A series of 3-aryl-substituted butenolides and butanolides has been prepared in a common short synthetic sequence from the corresponding aryl aldehydes. The 3-arylbutanolides are prepared by cyclisation of 3-aryl-3- cyano-1-propanols, obtained by selectiv

SUBSTITUTED OXIMES, HYDRAZONES AND OLEFINS AS NEUROKININ ANTAGONISTS

Compound represented by the structural formula STR1 or a pharmaceutically acceptable salt thereof, wherein: a is 0, 1, 2 or 3;b, d and e are independently 0, 1 or 2;R is H, C 1-6 alkyl,--OH or C 2-C 6 hydroxyalkyl; A is an optionally s