103753-78-2

Basic information

• Product Name: 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE
• Synonyms: 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE;3-(3,4-dichlorophenyl)dihydrofuran-2(3H)-one;2(3H)-Furanone, 3-(3,4-dichlorophenyl)dihydro-
• CAS NO: 103753-78-2
• Molecular Formula: C₁₀H₈Cl₂O₂
• Molecular Weight: 231.08
• Mol File: 103753-78-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 384.8 °C at 760 mmHg
• Flash Point: 173 °C
• Appearance: /
• Density: 1.406 g/cm³
• Vapor Pressure: 3.97E-06mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE(103753-78-2)
• EPA Substance Registry System: 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE(103753-78-2)

Safety Data

• Hazardous Substances Data: 103753-78-2(Hazardous Substances Data)

Usage

Description

3-(3,4-Dichloro-phenyl)-dihydro-furan-2-one is a synthetic chemical compound with the molecular formula C10H6Cl2O2. It is a white crystalline solid characterized by a melting point of 68-70°C and a boiling point of 317-318°C. 3-(3,4-DICHLORO-PHENYL)-DIHYDRO-FURAN-2-ONE is soluble in organic solvents such as acetone, chloroform, and ether, and is recognized for its potential as a fungicide and its use as a building block in the synthesis of various biological and pharmaceutical derivatives.

Uses

Used in Pharmaceutical Industry:
3-(3,4-Dichloro-phenyl)-dihydro-furan-2-one is used as an intermediate in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs. Its unique chemical structure allows it to be a versatile building block in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical industry, 3-(3,4-Dichloro-phenyl)-dihydro-furan-2-one is used as a potential fungicide. Its antimicrobial properties have been the subject of research for applications in protecting crops from fungal infections, thereby enhancing agricultural productivity.
Used in Specialty Chemicals Production:
3-(3,4-Dichloro-phenyl)-dihydro-furan-2-one also serves as a key component in the production of specialty chemicals. Its chemical properties make it suitable for various industrial applications where specific chemical interactions are required.

InChI:InChI=1/C10H8Cl2O2/c11-8-2-1-6(5-9(8)12)7-3-4-14-10(7)13/h1-2,5,7H,3-4H2

Upstream product

• 17739-45-6 2-(2-bromoethoxy)tetrahydropyran 
• 6725-44-6 methyl 2-(3,4-dichlorophenyl)acetate 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 40878-09-9 diethyl 2-(3,4-dichlorobenzylidene)malonate 
• 40878-08-8 cyanoester 
• 213380-60-0 cyanoalcohol 

Downstream Products

• 184969-75-3 alpha-(2-bromoethyl)-3,4-dichlorophenylacetic acid 
• 1131739-29-1 3-(3,4-dichloro-phenyl)-3-fluoro-dihydro-furan-2-one 
• 1093078-83-1 3-(3,4-dichloro-phenyl)-3-methyl-dihydro-furan-2-one 
• 213380-62-2 selenide 

Relevant articles and documents

PIPERIDINE DERIVATIVES AS NK3 ANTAGONISTS

The invention relates to a compound of formula wherein Ar1, Ar2, R1, R2, R3, R4, R5, and R5′ or to a pharmaceutically active salt thereof. The compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).

SUBSTITUTED OXIMES, HYDRAZONES AND OLEFINS AS NEUROKININ ANTAGONISTS

Compound represented by the structural formula STR1 or a pharmaceutically acceptable salt thereof, wherein: a is 0, 1, 2 or3; b, d and e are independently 0, 1 or 2;R is H, C 1-6 alkyl,--OH or C 2-C 6 hydroxyalkyl;A is an optionally su

SUBSTITUTED OXIMES, HYDRAZONES AND OLEFINS AS NEUROKININ ANTAGONISTS

Compound represented by the structural formula STR1 or a pharmaceutically acceptable salt thereof, wherein: a is 0, 1, 2 or 3;b, d and e are independently 0, 1 or 2;R is H, C 1-6 alkyl,--OH or C 2-C 6 hydroxyalkyl; A is an optionally s