1040918-09-9Relevant articles and documents
Synthesis of 2′-β-C-methyl-neplanocin derivatives as anti-HCV agents
Liao, Xibin,Butora, Gabor,Olsen, David B.,Carroll, Steven S.,McMasters, Daniel R.,Leone, Joseph F.,Stahlhut, Mark,Doss, George A.,Yang, Lihu,MacCoss, Malcolm
, p. 4149 - 4152 (2008/09/20)
The synthesis of 2′-β-C-methyl-neplanocin derivatives is described. The key intermediate cyclopentenyl alcohol 12 is prepared from sugar 5 in 12 steps. Coupling of 12 with appropriately protected purine, 7-deaza pyrimidine, uracil and pyrimidine bases via