105368-60-3

Basic information

• Product Name: GUGGULTETROL-20,EICOSAN-1,2,3,4-TETROL
• Synonyms: GUGGULTETROL-20,EICOSAN-1,2,3,4-TETROL
• CAS NO: 105368-60-3
• Molecular Formula: C20H42 O4
• Molecular Weight: 346.55
• Mol File: 105368-60-3.mol

Chemical Properties

• Boiling Point: 513.3±45.0 °C(Predicted)
• Appearance: /
• Density: 0.990±0.06 g/cm3(Predicted)
• PKA: 13.61±0.20(Predicted)
• CAS DataBase Reference: GUGGULTETROL-20,EICOSAN-1,2,3,4-TETROL(CAS DataBase Reference)
• NIST Chemistry Reference: GUGGULTETROL-20,EICOSAN-1,2,3,4-TETROL(105368-60-3)
• EPA Substance Registry System: GUGGULTETROL-20,EICOSAN-1,2,3,4-TETROL(105368-60-3)

Safety Data

• Hazardous Substances Data: 105368-60-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Guggultetrol-20, Eicosan-1,2,3,4-tetrol is used as an anti-inflammatory and antioxidant agent for its potential to alleviate various inflammatory conditions. Its traditional use in medicine, coupled with scientific evidence of its efficacy, positions it as a valuable component in the development of pharmaceutical formulations aimed at reducing inflammation and oxidative stress.
Used in Nutraceutical Industry:
In the realm of nutraceuticals, Guggultetrol-20, Eicosan-1,2,3,4-tetrol is utilized as a dietary supplement to promote overall health and well-being. Its ability to modulate inflammatory responses and provide antioxidant support makes it a sought-after ingredient in health products designed to support immune function and general wellness.
Used in Cosmetic Industry:
Guggultetrol-20, Eicosan-1,2,3,4-tetrol is employed as an active ingredient in cosmetic products for its skin health benefits. Its anti-inflammatory and antioxidant properties can contribute to skin rejuvenation, reducing the appearance of signs of aging, and promoting a healthy skin barrier, making it suitable for inclusion in skincare formulations.
Used in Research Applications:
In scientific research, Guggultetrol-20, Eicosan-1,2,3,4-tetrol serves as a subject of study for its potential role in inflammation management and other biological activities. Researchers investigate its mechanisms of action and interactions with biological systems to uncover new therapeutic possibilities and applications in medicine.
Each application leverages the unique properties of Guggultetrol-20, Eicosan-1,2,3,4-tetrol, highlighting its versatility and significance in various fields, from traditional medicine to modern therapeutics and wellness products.

Upstream product

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Relevant articles and documents

Convenient synthesis of D- and L-xylo-1,2,3,4-alkane tetrols from a D-gluco-configured common building block

D-gluco-Configured building block derived from d-(+)-gluconolactone has served as a common chiral template for the synthesis of enantiopure d- and l-xylo-configured 1,2,3,4-alkane tetrols. This has enabled synthesis of medicinally important guggultetrols and their enantiomers from a common starting point. Wittig and Grignard reactions are the key steps used for the incorporation of lipophilic chain.

SYNTHESIS AND PROPERTIES OF SOME STEREOISOMERIC LONG-CHAIN 1,2,3,4-TETROLS

Syntheses of 1,2S,3R,4R, 1,2S,3R,4S, 1,2R,3S,4R, and 1,2S,3S,4R-icosanetetrol, as well as of 1,2S,3S,4R-octadecanetetrol, are described, all based upon Wittig reactions of 1,2,3-protected pentodialdo-1,4-furanoses, serving as "chiral templates", with pentadecyl (or tridecyl) triphenylphosphorane, followed by catalytic hydrogenation, hydrolysis, and reduction.The tetrols, all forming liquid crystals on heating, are characterized spectroscopically and as their O-tetraacetates.The latter serve admirably for GLC-separation and -characterization of all non-enantiomeric tetrols.From the sign of rotation and GLC-comparison with the synthetic O-tetraacetates it follows that the 1,2,3,4-octadecanetetrol and 1,2,3,4-icosanetetrol, reported several years ago as the predominant members of a homologous series of tetrols derived from the gum-resin of Commiphora mukul, possess the 2S,3S,4R-configuration ("D-xylo").