105496-31-9

Basic information

• Product Name: N-FMOC-ETHANOLAMINE
• Synonyms: 2-(FMOC-AMINO)-ETHANOL;(2-HYDROXY-ETHYL)-CARBAMIC ACID 9H-FLUOREN-9-YLMETHYL ESTER;9-FLUORENYLMETHYL N-(2-HYDROXYETHYL)CARBAMATE;FMOC-2-AMINOETHANOL;FMOC-ETHANOLAMINE;FMOC-GLYCINOL;FMOC-GLY-OL;FMOC-NH-(CH2)2-OH
• CAS NO: 105496-31-9
• Molecular Formula: C₁₇H₁₇NO₃
• Molecular Weight: 283.32
• EINECS: 1533716-785-6
• Product Categories: Amino Acids;Amino Alcohols;Fmoc-Amino acid series
• Mol File: 105496-31-9.mol

Chemical Properties

• Melting Point: 144-147 °C(lit.)
• Boiling Point: 502.7 °C at 760 mmHg
• Flash Point: 257.8 °C
• Appearance: /
• Density: 1.238 g/cm³
• Vapor Pressure: 6.34E-11mmHg at 25°C
• Refractive Index: 1.609
• Storage Temp.: 2-8°C
• Solubility: DMSO, Methanol
• PKA: 11.38±0.46(Predicted)
• CAS DataBase Reference: N-FMOC-ETHANOLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-FMOC-ETHANOLAMINE(105496-31-9)
• EPA Substance Registry System: N-FMOC-ETHANOLAMINE(105496-31-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 105496-31-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
N-FMOC-ETHANOLAMINE is used as a protecting group for amino acids during peptide synthesis. The Fmoc group provides a stable and easily removable protection for the amino group, allowing for the stepwise assembly of peptides without racemization or side reactions.
Used in Chemical Synthesis:
N-FMOC-ETHANOLAMINE is used as a building block in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its reactivity and compatibility with various reaction conditions make it a valuable intermediate in the development of new molecules.
Used in Material Science:
N-FMOC-ETHANOLAMINE is used in the preparation of amphiphilic lactosides, which are important components in the development of self-assembling materials and drug delivery systems. These lactosides can form micelles, liposomes, or other nanostructures with potential applications in targeted drug delivery and imaging.

InChI:InChI=1/C17H17NO3/c19-10-9-18-17(20)21-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16,19H,9-11H2,(H,18,20)

Upstream product

• 2002-24-6 2-amino-ethanol hydrochloride 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 29022-11-5 N-(fluoren-9-ylmethoxycarbonyl)glycine 
• 141-43-5 ethanolamine 
• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 

Downstream Products

• 156939-62-7 (9H-fluoren-9-yl)methyl(2-oxoethyl)carbamate 
• 153765-09-4 9-fluorenylmethoxycarbonyl-O-(4,4'-dimethoxytrityl)ethanolamine 
• 340187-12-4 (9H-fluoren-9-yl)methyl (2-bromoethyl)carbamate 

Relevant articles and documents

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