105512-06-9

Basic information

• Product Name: Clodinafop-propargyl
• Synonyms: propynyl (r)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy] phenoxy]propanoate;Topik;CLODINAFOP-PROPARGYL;CLODINAFOP-PROPARGYL ESTER;cga-184927;CLODINAFOP-PROPARGYL PESTANAL;Propanoic acid, 2-4-(5-chloro-3-fluoro-2-pyridinyl)oxyphenoxy-, 2-propynyl ester, (2R)-;clodinafop-propargyl ester (bsi, pa e-iso)
• CAS NO: 105512-06-9
• Molecular Formula: C17H13ClFNO4
• Molecular Weight: 349.74
• Product Categories: Alpha sort;C;CAlphabetic;CI - CLPesticides&Metabolites;Herbicides;Pesticides&Metabolites;Phenoxy structure;Agro-Products;Aromatics;Chiral Reagents;Heterocycles
• Mol File: 105512-06-9.mol

Chemical Properties

• Melting Point: 48-57°C
• Boiling Point: 432.7 °C at 760 mmHg
• Flash Point: 215.5 °C
• Appearance: /
• Density: 1.326 g/cm³
• Storage Temp.: 0-6°C
• PKA: -1.54±0.32(Predicted)
• BRN: 8857008
• CAS DataBase Reference: Clodinafop-propargyl(CAS DataBase Reference)
• NIST Chemistry Reference: Clodinafop-propargyl(105512-06-9)
• EPA Substance Registry System: Clodinafop-propargyl(105512-06-9)

Safety Data

• Hazard Codes: Xn;N,N,Xn
• Statements: 20/22-43-50/53-48/22
• Safety Statements: 36/37-60-61-46-24
• RIDADR: UN 2811
• WGK Germany: 3
• Hazardous Substances Data: 105512-06-9(Hazardous Substances Data)

Usage

Uses

1. Used in Agriculture:
Clodinafop-propargyl is used as a systemic herbicide for the control of annual grass weeds in cereal crops. It is particularly effective against post-emergent weeds such as selected grasses and does not act on broad-leaved weeds. The herbicide is applied to the foliar parts of the weeds, where it is absorbed through the leaves and translocated to the meristematic growing points of the plant.
2. Used in Wheat Crop Protection:
Clodinafop-propargyl is used as a herbicide for weed control in wheat, providing moderate control of Italian rye-grass and controlling grass weeds such as wild oats, rough meadow-grass, green foxtail, barnyard grass, Persian darnel, and volunteer canary seed.
3. Used in Crop Compatibility:
Clodinafop-propargyl is suitable for use on various crops, including all varieties of wheat, autumn-sown spring wheat, rye, triticale, and durum wheat.
4. Used in Chemical Synthesis:
Clodinafop-propargyl can inhibit the synthesis of ester-like biology, making it useful for controlling various types of weeds, such as amur foxtail, oat grass, avena sterilis, and green bristlegrass.

Mode of action

Clodinafop-propargyl is to inhibit the activity of acetyl-CoA carboxylase in plants. It is a systemic conductive herbicide, absorbed by the leaves and sheaths of plants, transmitted by phloem, and accumulated in meristems of plants. In this case, acetyl-CoA carboxylase is inhibited, and fatty acid synthesis is stopped. So cell growth and division cannot proceed normally, and lipid-containing structures such as membrane systems are destroyed, leading to plant death.

Toxicity evaluation

a) Mammalian toxicity : WHO Classification : Class III slightly hazardous”b) Environmental toxicity : It is non-toxic to fish, birds and bees.Shelf life :Two years under normal storage conditions (Tech grade and Formulation)

InChI:InChI=1/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1

Upstream product

• 114420-56-3 clodinafop 
• 107-19-7 propargyl alcohol 
• 89402-43-7 5-chloro-2,3-difluoropyridine 
• 94050-90-5 (R)-2-(4-hydroxyphenoxy)propionic acid 
• 624-65-7 2-propynyl chloride 

Relevant articles and documents

Synthesis method of clodinafop-propargyl

The invention relates to the field of chemical engineering, and discloses a synthesis method of clodinafop-propargyl. The method comprises the following steps of: dissolving DHPPA in an organic solvent, heating to a temperature of 50 DEG C, adding an anti

NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND

An object of the present invention is to provide a compound having the controlling activity on a noxious arthropod, and a noxious arthropod controlling agent containing an amide compound of formula (I): wherein X represents a nitrogen atom or a CH group, p represents 0 or 1, A represents a tetrahydrofuranyl group or the like, R1, R2, R3, R4, R5, R6 and R7 represent a hydrogen atom or the like, n represents 1 or 2, Y represents an oxygen atom or the like, m represents any integer of 0 to 7, and Q represents a C1-8 chain hydrocarbon group optionally having a phenyl group or the like, has the excellent noxious arthropod controlling effect.

Preparation method of clodinafop propargyl

The invention relates to a preparation method of clodinafop propargyl used for controlling grassy weeds in wheat fields. R-2-(p-hydroxyphenoxy)propionic acid is taken as a raw material and has a reaction with caustic alkali in water and an aprotic polar s

LIQUID FORMULATIONS

The present invention relates to a liquid formulation comprising a) agrochemically active salts of 2-iodo-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]benzenesulfonamide, and b) one or more non-polar organic solvents selected from the group of the C6-C16-aromatics mixture the Solvesso series (Exxon) and/or the Caromax series (Carless), and also ?optionally further non-polar organic solvents. The liquid formulation is suitable for crop protection.

A new method for one-pot synthesis of aryloxyphenoxypropionate herbicides using 2,4,6-trichloro-1,3,5-triazine and (n-BU)4NI as a homogeneous catalyst

The one-pot reaction of halo-heterocycle, (R)-4-hydroxyphenoxy propionic acid and an alcohol, amine or sulfonamide is described as an efficient method for the synthesis of aryloxyphenoxy propionate hrerbicides by using 2,4,6-trichloro-1,3,5-triazine in the presence of (n-BU) 4NI, as a homogeneous catalyst under mild conditions. The present procedure offers several advantages, such as good yields, short reaction times and easy workup.

A facile synthesis of novel optically active R,R-2-(4-(2-(4-(5-chloro-3- halo-pyridin-2-yloxy)-phenoxy)-propionyloxy)-phenoxy)-propionic acid esters using cyanuric chloride as potential herbicide

A facile method for the synthesis of a new series of R,R-2-(4-(2-(4-(5- chloro-3-halopyridin-2-yloxy)-phenoxy)-propionyloxy)-phenoxy)-propionic acid ester derivatives containing a halo-substituted pyridine carrying two R,R chiral centers from (R)-2-(4-hyd

Solid adjuvants

The present invention relates to a solid adjuvant comprising a) one or more surfactants of the formula (I), Ar—O—(CHR1—CHR2—O—)y—R3??(I) where Ar is aryl which is substituted by at least two (C1-C30)alkyl radicals, R1 is H or (C1-C6)alkyl, R2 is H or (C1-C6)alkyl, R3 is H, an unsubstituted or substituted (C1-C30) hydrocarbon radical, a sulfonate radical, a phosphonate radical or an acyl radical, and y is an integer from 1 to 100, and b) one or more fatty acid esters. The adjuvant is particularly suitable in the field of crop protection.

Herbicidal compositions

The present invention relates to a herbicidal composition comprising a) one or more herbicidal active substances, b) one or more surfactants other than silicone surfactants, and c) one or more humectants. The composition according to the invention is outstandingly suitable for controlling a variety of harmful plants.

Herbicidal composition

The present invention relates to a herbicidal composition, comprising A) one or more compounds of the formula (I) 1in which Hal1 and Hal2 are identical or different halogen atoms, R1 is H, a cation or a C1-C20-carbon-containing radical and B) one or more surfactants, comprising as structural element at least 12 alkylene oxide units.