105776-76-9

Basic information

• Product Name: (2S)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid
• Synonyms: (2S)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid;(S)-2-(1-oxoisoindolin-2-yl)-3-phenylpropanoic acid
• CAS NO: 105776-76-9
• Molecular Formula: C₁₇H₁₅NO₃
• Molecular Weight: 281.3059
• Mol File: 105776-76-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 516.5±50.0 °C(Predicted)
• Appearance: /
• Density: 1.317±0.06 g/cm3(Predicted)
• PKA: 3.50±0.10(Predicted)
• CAS DataBase Reference: (2S)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid(105776-76-9)
• EPA Substance Registry System: (2S)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid(105776-76-9)

Safety Data

• Hazardous Substances Data: 105776-76-9(Hazardous Substances Data)

Usage

General Description

(2S)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid is a chemical compound primarily used in the field of medicine. It is a derivative of the amino acid phenylalanine and is known for its potential pharmaceutical applications. (2S)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid has been studied for its potential role in treating various medical conditions, including neurological disorders and mood disorders. Its chemical structure makes it a promising candidate for drug development, and it is currently undergoing further research and development to explore its potential therapeutic uses.

Upstream product

• 63-91-2 L-phenylalanine 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 4122-56-9 methyl o-formylbenzoate 

Downstream Products

• 137281-92-6 (3S)-4-cyclohexyl-2-hydroxy-3-<<(2S)-4-methyl-2-<<(2S)-2-(1-oxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionyl>amino>pentanoyl>amino>butyric acid isopropyl ester 
• 137281-92-6 (2S,3S)-4-Cyclohexyl-2-hydroxy-3-{(S)-4-methyl-2-[(S)-2-(1-oxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-pentanoylamino}-butyric acid isopropyl ester 
• 137282-11-2 (2S)-4-methyl-2-<<(2S)-2-(1-oxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionyl>amino>pentanoic acid methyl ester 
• 137282-12-3 (2S)-4-methyl-2-<<(2S)-2-(1-oxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionyl>amino>pentanoic acid 
• 137281-94-8 (3S)-4-cyclohexyl-2-hydroxy-3-<<(2S)-3-(1H-imidazol-4-yl)-2-<<(2S)-2-(1-oxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionyl>amino>propionyl>amino>butyric acid methyl ester 
• 137282-01-0 (3S)-4-cyclohexyl-2-hydroxy-3-<<(2S)-2-<<(2S)-2-(1-oxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionyl>amino>hexanoyl>amino>butyric acid isopropyl ester 
• 137282-00-9 (3S)-4-cyclohexyl-2-hydroxy-3-<<(2S)-2<<(2S)-2-(1-oxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionyl>amino>pentanoyl>amino>butyric acid isopropyl ether 

Relevant articles and documents

Synthesis and antimicrobial activity of some isoindolin-1-ones derivatives

A range of N-substituted isoindolin-1-ones was prepared and their potential as novel antimicrobial agents was investigated. MIC values for active compounds were determined and reported. (C) 2000 Published by Elsevier Science Ltd.

USP30 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of USP30, and the treatment of USP30-mediated disorders.