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High purity L-Phenylalanine with high quality cas:63-91-2
Cas No: 63-91-2
USD $ 7.0-20.0 / Kilogram 1 Kilogram 99999 Kilogram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
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No Data No Data 1500 Metric Ton/Year Siwei Development Group Ltd. Contact Supplier
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L-PHENYLALANINE
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63-91-2 Usage

References

[1] http://www.umm.edu/health/medical/altmed/supplement/phenylalanine
[2] Xueqin Song , Philip L. Lorenzi , Christopher P. Landowski , Balvinder S. Vig , John M. Hilfinger , Gordon L. Amidon (2005) Amino Acid Ester Prodrugs of the Anticancer Agent Gemcitabine:? Synthesis, Bioconversion, Metabolic Bioevasion, and hPEPT1-Mediated Transport, 2, 157-167.

Definition

ChEBI: The L-enantiomer of phenylalanine.

Purification Methods

Likely impurities are leucine, valine, methionine and tyrosine. Crystallise L-phenylalanine from water by adding 4volumes of EtOH. Dry it in vacuo over P2O5. Also crystallise it from saturated refluxing aqueous solutions at neutral pH, or 1:1 (v/v) EtOH/water solution, or conc HCl. It sublimes at 176-184o/0.3mm with 98.7% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2156-2175 1961, Beilstein 14 IV 1552.]

Air & Water Reactions

Water soluble. Aqueous solutions are weak acids.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition L-Phenylalanine emits toxic fumes of nitrogen oxides.

General Description

Odorless white crystalline powder. Slightly bitter taste. pH (1% aqueous solution) 5.4 to 6.

Uses

L-Phenylalanine is an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded amino acids, which in turn is converted to L-DOPA and further conv erted into dopamine, norepinephrine, and epinephrine. L-Phenylalanine is produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.

Description

Phenylalanie is an essential amino acid and it is the precursor of the amino acid tyrosine. The body cannot make phenylalanie but it needs phenylalanie to produce proteins. Thus, human needs to obtain phenylalanie from food. 3 forms of phenylalanie are found in the nature: D-phenylalanine, L-phenylalanine, and DL-phenylalanine. Among these three forms, L-phenylalanine is the natural form found in most foods that containing proteins, including beef, poultry, pork, fish, milk, yogurt, eggs, cheeses, soy products, and certain nuts and seeds. The form of phenylalanine determines its application. It is suggested that L-phenylalanine can strengthen the effect of UVA radiation for people with vitiligo, in which L-phenylalanine may lead to darkening or repigmentation of the white patches, particularly on the face. The neurotransmitters L-phenylalanine affects help reduce hunger, improve memory, lessen the symptoms of ADHD and Parkinson's disease, and ease chronic pain, according to the UMMC research. Thus, L-phenylalanine is used in the manufacture of food and drink products and sold as a nutritional supplement for its reputed analgesic and antidepressant effects. L-phenylalanine is also suggested as an intermediate for anti-cancer drugs. A few small studies showed promise using L-Phenylalanine to manage alcohol withdrawal and ease PMS symptoms. It is also used in artificial sweeteners such as aspartame.

Reactivity Profile

L-Phenylalanine may be light sensitive. Act as weak acids in solution.

Chemical Properties

White crystalline powder

Fire Hazard

Flash point data for L-Phenylalanine are not available; however, L-Phenylalanine is probably combustible.
InChI:InChI:1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)

63-91-2 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Vetec (V900489)  L-Phenylalanine  Vetec reagent grade, ≥98% 63-91-2 V900489-100G 145.08CNY Detail
Vetec (V900489)  L-Phenylalanine  Vetec reagent grade, ≥98% 63-91-2 V900489-25G 59.67CNY Detail
USP (1530503)  L-Phenylalanine  United States Pharmacopeia (USP) Reference Standard 63-91-2 1530503-200MG 4,662.45CNY Detail
Sigma (78019)  L-Phenylalanine  BioUltra, ≥99.0% (NT) 63-91-2 78019-500G 4,563.00CNY Detail
Sigma (78019)  L-Phenylalanine  BioUltra, ≥99.0% (NT) 63-91-2 78019-100G 1,471.86CNY Detail
Sigma (78019)  L-Phenylalanine  BioUltra, ≥99.0% (NT) 63-91-2 78019-25G 473.85CNY Detail
Sigma (P8740)  L-Phenylalanine  PharmaGrade, Ajinomoto, EP, JP, USP, manufactured under appropriate GMP controls for Pharma or Biopharmaceutical production, suitable for cell culture 63-91-2 P8740-25KG 109,980.00CNY Detail
Sigma (P8740)  L-Phenylalanine  PharmaGrade, Ajinomoto, EP, JP, USP, manufactured under appropriate GMP controls for Pharma or Biopharmaceutical production, suitable for cell culture 63-91-2 P8740-10KG 48,391.20CNY Detail
Sigma (P8740)  L-Phenylalanine  PharmaGrade, Ajinomoto, EP, JP, USP, manufactured under appropriate GMP controls for Pharma or Biopharmaceutical production, suitable for cell culture 63-91-2 P8740-1KG 8,798.40CNY Detail
Sigma (P8740)  L-Phenylalanine  PharmaGrade, Ajinomoto, EP, JP, USP, manufactured under appropriate GMP controls for Pharma or Biopharmaceutical production, suitable for cell culture 63-91-2 P8740-100G 2,331.81CNY Detail
Sigma (P5482)  L-Phenylalanine  from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0% 63-91-2 P5482-1KG 6,364.80CNY Detail
Sigma (P5482)  L-Phenylalanine  from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0% 63-91-2 P5482-100G 1,122.03CNY Detail

63-91-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name L-phenylalanine

1.2 Other means of identification

Product number -
Other names Benzenepropanethioic acid,S-phenyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food additives -> Flavoring Agents
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:63-91-2 SDS

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