105785-75-9

Basic information

• Product Name: BIS(2,2-DIMETHYLPROPOXY)TRIPHENYLPHOSPHORANE
• Synonyms: BIS(2,2-DIMETHYLPROPOXY)TRIPHENYLPHOSPHORANE
• CAS NO: 105785-75-9
• Molecular Formula: C₂₈H₃₇O₂P
• Molecular Weight: 436.565941
• Mol File: 105785-75-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BIS(2,2-DIMETHYLPROPOXY)TRIPHENYLPHOSPHORANE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(2,2-DIMETHYLPROPOXY)TRIPHENYLPHOSPHORANE(105785-75-9)
• EPA Substance Registry System: BIS(2,2-DIMETHYLPROPOXY)TRIPHENYLPHOSPHORANE(105785-75-9)

Safety Data

• Hazardous Substances Data: 105785-75-9(Hazardous Substances Data)

Upstream product

• 75-84-3 2,2-dimethyl-propanol-1 
• 58477-00-2 diethylazodicarboxylate - triphenylphosphine (DEAD-Ph₃P) 
• 791-28-6 Triphenylphosphine oxide 
• 1034-39-5 dibromotriphenylphosphorane 
• 603-35-0 triphenylphosphine 
• 3710-27-8 lithium tert-butoxide 
• 105785-73-7 (neopentyloxy)triphenylphosphonium bromide 

Relevant articles and documents

Development of a redox-free Mitsunobu reaction exploiting phosphine oxides as precursors to dioxyphosphoranes

The development of the first redox-free protocol for the Mitsunobu reaction is described. This has been achieved by exploiting triphenylphosphine oxide-the unwanted by-product in the conventional Mitsunobu reaction-as the precursor to the active P(v) coupling reagent. Multinuclear NMR studies are consistent with hydroxyl activation via an alkoxyphosphonium salt.

Bis(neopentyloxy)triphenylphosphorane: A Versatile, Nonalkylating Cyclodehydration Reagent

Bis(neopentyloxy)triphenylphosphorane (BNTP; 31P δ -58.3) is prepared in 48percent yield by reaction of 2 equiv of lithium neopentoxide with dibromotriphenylphosphorane in anhydrous dichloromethane from -78 to 25 deg C.BNTP smoothly converts a variety of diols, 2-aminoethanol, and 4-mercaptobutanol to the corresponding heterocycles in excellent yields (>95percent) by 13C and 31P NMR analysis.