1067229-00-8Relevant articles and documents
2-Arylpyrimidines: Novel CRF-1 receptor antagonists
Yoon, Taeyoung,De Lombaert, Stephane,Brodbeck, Robbin,Gulianello, Michael,Krause, James E.,Hutchison, Alan,Horvath, Raymond F.,Ge, Ping,Kehne, John,Hoffman, Diane,Chandrasekhar, Jayaraman,Doller, Dario,Hodgetts, Kevin J.
scheme or table, p. 4486 - 4490 (2009/04/08)
The design, synthesis and structure-activity relationship studies of a novel series of CRF-1 receptor antagonists, the 2-arylpyrimidines, are described. The effects of substitution on the aromatic ring and the pyrimidine core on CRF-1 receptor binding wer