107832-61-1Relevant articles and documents
Preparation of Thioanisole Biscarbanion and C-H Lithiation/Annulation Reactions for the Access of Five-Membered Heterocycles
Zhu, Ranran,Liu, Zheyuan,Chen, Jie,Xiong, Xiaoyu,Wang, Yuntao,Huang, Lin,Bai, Jinshan,Dang, Yanfeng,Huang, Jianhui
supporting information, p. 3161 - 3165 (2018/06/11)
The synthesis, isolation, and X-ray structure of a thioanisole-based trilithium complex are reported. On the basis of the double-lithiation strategy, two novel synthetic methodologies have been developed under mild reaction conditions (room temperature): (1) reactions of lithiated thioanisoles with nitriles give benzoisothiazoles via a [3 + 2]-type of approach with two new bond formations and (2) formation of benzothiophenes from thioanisoles and amides through a [4 + 1] pattern forming 4 new chemical bonds.
METALATION REACTIONS. IX. DILITHIATION OF AROMATIC THIOETHERS
Cabiddu, Salvatore,Floris, Constantino,Melis, Stefana
, p. 4625 - 4628 (2007/10/02)
Direct dimetalation of aromatic thioethers gives with good yield the dilithiated species 3, 4, 17, 18, 25, 26.The first four species allowed the simultaneous introduction of an electrophile in the thiomethyl group and in the ring, while the last two species undergo disubstitution in the ring.
