111153-74-3

Basic information

• Product Name: 1-PHENYLPIPERIDINE-4-CARBALDEHYDE
• Synonyms: 1-PHENYLPIPERIDINE-4-CARBALDEHYDE
• CAS NO: 111153-74-3
• Molecular Formula: C₁₂H₁₅NO
• Molecular Weight: 189.25
• Mol File: 111153-74-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 1-PHENYLPIPERIDINE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYLPIPERIDINE-4-CARBALDEHYDE(111153-74-3)
• EPA Substance Registry System: 1-PHENYLPIPERIDINE-4-CARBALDEHYDE(111153-74-3)

Safety Data

• Hazardous Substances Data: 111153-74-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-Phenylpiperidine-4-carbaldehyde is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its ability to form derivatives with potential therapeutic properties makes it a valuable building block in drug development.
Used in the Preparation of Cardiotonic Agents:
1-Phenylpiperidine-4-carbaldehyde is used as a reagent for the preparation of 2-phenylthiazolidine derivatives, which are known to have cardiotonic properties. These derivatives can be employed as active ingredients in the development of medications aimed at improving heart function and treating various cardiovascular conditions.

Upstream product

• 19125-34-9 1-phenylpiperidin-4-one 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 697306-45-9 (1-phenylpiperidin-4-yl)methanol 
• 1126-09-6 4-carbethoxypiperidine 
• 247022-37-3 ethyl 1-phenylpiperidine-4-carboxylate 
• 591-50-4 iodobenzene 

Downstream Products

• 111153-75-4 2-(1-phenylpiperidin-4-yl)acetaldehyde 
• 111153-82-3 N-methyl-2-(2-(2-(1-phenyl-4-piperidyl)propoxy)phenyl)thiazolidine-3-carbothioamide 
• 111181-27-2 N-methyl-2-(2-(2-(1-phenyl-4-piperidyl)ethoxy)phenyl)thiazolidine-3-carbothioamide 
• 111181-26-1 1-phenyl-4-piperidinepropanol O-tosylate 
• 111153-79-8 1-phenyl-4-piperidineethanol O-tosylate 
• 111153-81-2 2-(2-(1-phenyl-4-piperidyl)propoxy)benzaldehyde 
• 111153-80-1 2-(2-(1-phenyl-4-piperidyl)ethoxy)benzaldehyde 
• 111153-78-7 1-phenyl-4-piperidinepropanol 
• 111153-76-5 2-(1-phenylpiperidin-4-yl)ethanol 
• 111153-77-6 3-(1-phenyl-4-piperidyl)-2-propenal 

Relevant articles and documents

NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF

The invention provides compounds for inhibiting glucosylceramidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds.

TRICYCLIC COMPOUND SERVING AS IMMUNOMODULATOR

Provided are compounds of formula I and formula II or pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof. The compounds of formula I and formula II or the pharmaceutically acceptable salts of the compounds provide indole 2,3-dioxygenase (IDO) inhibitory activity and are capable of treating IDO-mediated immunosuppressive diseases, such as infectious diseases or cancer.

AMINE COMPOUNDS

The present invention provide a compound of the formula:wherein ring A represents an aromatic ring optionally having substituents; B, Y and Ya are the same or different and each represents a bond, etc.; R1 and R2 are the same or different and each represents a hydrogen atom, etc.; R3 represents a hydrogen atom, etc.; R4 and R5 are the same or different and each represents a hydrogen, etc.; R6 represents an indolyl group optionally having substituents; and Z and Za are the same or different and each represents a hydrogen atom, etc.; or a salt thereof or a prodrug thereof, having a somatostatin receptor binding inhibition activity and is useful for preventing and/or treating diseases associated with somatostatin.