111466-75-2 Usage
General Description
1,2-dioctanoylthiophosphatidylcholine is a synthetic phospholipid with potential therapeutic applications. It is a derivative of phosphatidylcholine and contains two octanoyl chains and an attached thiophosphate group. This chemical has been studied for its ability to improve the stability and effectiveness of liposomal formulations used in drug delivery. Additionally, 1,2-dioctanoylthiophosphatidylcholine has shown promise in the treatment of cancer, as it has been found to enhance the delivery and efficacy of anticancer agents. 1,2-dioctanoylthiophosphatidylcholine has also demonstrated anti-inflammatory and antioxidant properties, making it a potential candidate for the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 111466-75-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,4,6 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 111466-75:
(8*1)+(7*1)+(6*1)+(5*4)+(4*6)+(3*6)+(2*7)+(1*5)=102
102 % 10 = 2
So 111466-75-2 is a valid CAS Registry Number.
InChI:InChI=1/C24H48NO8P/c1-6-8-10-12-14-16-23(26)30-20-22(33-24(27)17-15-13-11-9-7-2)21-32-34(28,29)31-19-18-25(3,4)5/h22H,6-21H2,1-5H3
111466-75-2Relevant articles and documents
Selective Acylation of Nucleosides, Nucleotides, and Glycerol-3-phosphocholine in Water
Fernández-García, Christian,Powner, Matthew W.
, p. 78 - 83 (2017)
A convenient selective synthesis of 2′,3′-di-O-acetyl-nucleotide-5′-phosphates, 2′,3′-di-O-acetyl-nucleotide-5′-triphosphates and 2′,3′,5′-tri-O-acetyl-nucleosides in water has been developed. Furthermore, a long-chain selective glycerol-3-phosphocholine diacylation is elucidated. These reactions are environmentally benign, rapid, high yielding, and the products are readily purified. Importantly, this reaction may indicate a prebiotically plausible reaction pathway for the selective acylation of key metabolites to facilitate their incorporation into protometabolism.
