111818-56-5

Basic information

• Product Name: Butanoic acid, 2-ethyl-2-[(1-oxo-2-propenyl)amino]- (9CI)
• Synonyms: Butanoic acid, 2-ethyl-2-[(1-oxo-2-propenyl)amino]- (9CI)
• CAS NO: 111818-56-5
• Molecular Formula: C9H15NO3
• Molecular Weight: 185.22
• Mol File: 111818-56-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Butanoic acid, 2-ethyl-2-[(1-oxo-2-propenyl)amino]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-ethyl-2-[(1-oxo-2-propenyl)amino]- (9CI)(111818-56-5)
• EPA Substance Registry System: Butanoic acid, 2-ethyl-2-[(1-oxo-2-propenyl)amino]- (9CI)(111818-56-5)

Safety Data

• Hazardous Substances Data: 111818-56-5(Hazardous Substances Data)

Upstream product

• 143-33-9 sodium cyanide 
• 814-68-6 acryloyl chloride 
• 96-22-0 pentan-3-one 

Relevant articles and documents

A ONE-POT TRANSFORMATION OF KETONES INTO N-(METH)ACRYLOYL-2-AMINO ACIDS

A synthetic sequence for the preparation of N-(meth)acryloyl-2-amino acids is outlined which involves transformation of a ketone successively into an aminonitrile and a (meth)acrylamidonitrile, followed by selective hydrolysis of the nitrile function.All reactions are performed in aqueous media, in one reaction vessel, and in a stepwise manner without isolation of any intermadiate products.

Method of preparing N-acryloyl-α-amino acids

A novel, one-pot procedure for the preparation of N-acryloyl-α-amino acids involves the steps of: (i) reacting a ketone, an ammonium salt, and a cyanide salt in water, optionally in the presence of ammonium hydroxide and a co-solvent, to form an aminonitrile; (ii) acryloylating the aminonitrile in aqueous media to afford an acrylamidonitrile; and (iii) hydrolyzing with aqueous acid the acrylamidonitrile to provide the N-acryloyl-α-amino acid.