Xi:Irritant;112-37-8Relevant articles and documents
A trehalose ester from Lancea tibetica
Liu, Shi-Jun,Liao, Zhi-Xin,Liu, Chao,Qu, Yan-Bo
, p. 1613 - 1618 (2014)
A phytochemical study of the 95% ethanolic extract of the whole plant of Lancea tibetica Hook. f. et Thoms. led to the isolation of a new trehalose ester, 6-O-undecanoyl-α,β-trehalose (1), along with 23 known compounds (2-24), of which compounds 2-17 were isolated from this plant for the first time. The structures of these compounds were established on the basis of spectroscopic methods. Compound 1 was evaluated for their in vitro anti-proliferative activities against MCF-7, NCI-H460 and Hep-G2 tumour cell lines. Compound 1 exhibited potent inhibitory activity against NCI-H460 cell growth, in contrast to moderate cytotoxic activity against MCF-7 and Hep-G2 cells.
Nanocoating of Hydrophobic Mesoporous Silica around MIL-101Cr for Enhanced Catalytic Activity and Stability
Ying, Jie,Herbst, Annika,Xiao, Yu-Xuan,Wei, Hao,Tian, Ge,Li, Zhaofei,Yang, Xiao-Yu,Su, Bao-Lian,Janiak, Christoph
, p. 899 - 902 (2018)
The metal-organic framework (MOF) MIL-101Cr was readily encapsulated by a very thin shell (around 30 nm) of hydrophobic mesoporous silica, which replicates the irregular shape of the MOF nanocrystals. Such a silica shell facilitates the diffusion of hydrophobic reactants with enhancement of the catalytic activity of the MOF and significantly improved catalytic stability of the MOF in the oxidation of indene.
Colloidal Nobel Metal Catalysts Protected by Surfactant Micelles. Regio-Selectivity in the Hydrogenation of Unsaturated Fatty Acids in Organized Media
Toshima, Naoki,Takahashi,Tadahito
, p. 573 - 576 (1988)
Colloidal dispersions of platinum and palladium protected by nonionic surfactants were prepared by photo-irradiation.They work as active catalysts for the hydrogenation of unsaturated fatty acids and their sodium salts.The regio-selectivity was observed in the hydrogenation in the organized media which surround the colloidal particles.Thus, 10-undecenoic acid was more rapidly hydrogenated than 2-undecenoic acid
One-pot sequences of reactions with sol-gel entrapped opposing reagents: An enzyme and metal-complex catalysts
Gelman, Faina,Blum, Jochanan,Avnir, David
, p. 14460 - 14463 (2002)
We extend our sol-gel methodology of one-pot sequences of reactions with opposing reagents to an enzyme/metal-complex pair. Sol-gel entrapped lipase and sol-gel entrapped RhCl[P(C6H5)3]3 or Rh2Co2(CO)12 were used for one-pot esterification and C-C double bond hydrogenation reactions, leading to saturated esters in good yields. When only the enzyme is entrapped, the homogeneous catalysts quench its activity and poison it. Thus, when 10-undecenoic acid and 1-pentanol were subjected in one pot to the entrapped lipase and to homogeneously dissolved RhCl[P(C6H5)3]3 under hydrogen pressure, only 7% of the saturated 1-pentyl undecanoate was obtained. The yield jumped 6.5-fold when both the enzyme and the catalyst were immobilized separately in silica sol-gel matrixes. Similar one-pot esterifications and hydrogenations by sol-gel entrapped lipase and heterogenized rhodium complexes were carried out successfully with the saturated nonoic, undecanoic, and lauric acids together with several saturated and unsaturated alcohols. The use of (S)-(-)-2-methylbutanol afforded an optically pure ester. The heterogenized lipase is capable of inducing asymmetry during esterification with a prochiral alcohol. Both the entrapped lipase and the immobilized rhodium catalysts can be recovered simply by filtration and recycled in further runs without loss of catalytic activity.
Tempo-mediated oxidation of primary alcohols to carboxylic acids by exploitation of ethers inan aqueous-organicbiphase system
Mei, Zhen-Wu,Ma, Li-Jian,Kawafuchi, Hiroyuki,Okihara, Takumi,Inokuchi, Tsutomu
, p. 1000 - 1002 (2009)
Expeditious and benign methods for primary alcohol- carboxylicacid conversions with TEMPO were developed in abiphasic system composed of aslightlymiscible ether (THP) and aqueous layer. Easily available co-oxidants such as Py-HBr3, Bu4NBr3, and electrooxidation were successfully applied to generate N-oxoammonium species as a recyclable catalyst.
CYCLOPHOSPHAZENIC POLYPODANTS: A NEW CLASS OF POWERFUL METAL CATION COMPLEXING AGENTS AND PHASE-TRANSFER CATALYSTS
Landini, D.,Maia, A.,Corda, L.,Maccioni, A.,Podda, G.
, p. 5781 - 5784 (1989)
Cyclophosphazenic polypodants are found to be powerful complexing agents of alkali metal salts and very efficient phase-transfer catalysts in nucleophilic substitution, alkylation, reduction and oxidation reactions.
A Mild, General, Metal-Free Method for Desulfurization of Thiols and Disulfides Induced by Visible-Light
Qiu, Wenting,Shi, Shuai,Li, Ruining,Lin, Xianfeng,Rao, Liangming,Sun, Zhankui
supporting information, p. 1255 - 1258 (2021/05/05)
A visible-light-induced metal-free desulfurization method for thiols and disulfides has been explored. This radical desulfurization features mild conditions, robustness, and excellent functionality compatibility. It was successfully applied not only to the desulfurization of small molecules, but also to peptides.
Synthetic method of acid compound
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Paragraph 0028-0033; 0066-0081, (2020/08/25)
The invention belongs to the field of organic synthesis, and particularly relates to a synthetic method of an acid compound. An acid anhydride compound and an alkyl bromide or a functionalized alkyl bromide are subjected to a cross-electrophilic coupling reaction to synthesize an acid compound, so that the application of the alkyl bromide in the cross-electrophilic coupling reaction is expanded, and a novel non-traditional method for chemically and selectively constructing a carbon-carbon bond through a decarburization process is provided. The synthesis method is simple, economic, green and environment-friendly, and has wider applicability or is suitable for large-scale production.
Process for the preparation of fatty acids
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Paragraph 0179-0206; 0213-0215, (2020/09/04)
The invention discloses a method for preparing fatty acid. The method comprises the following steps: providing a first reactant which is a furan compound containing an carbonyl group; providing a second reactant which is a compound containing a carboxyl group, an ester group or an anhydride group and can participate in a condensation reaction with the carbonyl group of the first reactant; allowingthe first reactant and the second reactant to participate in a first condensation reaction, and allowing a C=O bond of the carbonyl group of the first reactant to be connected with alpha carbon of the carbonyl group of the second reactant and to be converted into a C=C bond so as to form a condensation product; and carrying out a second-step reaction under hydrogen pressure in the presence of a co-catalytic system of a hydrogenation catalyst and Lewis acid, opening a furan ring of the condensation product, carrying out hydrodeoxygenation at the same time, removing all oxygen except for oxygenin the carboxyl group, and allowing a carbon chain to be saturated so as to obtain the fatty acid.
PRODUCTION METHOD OF AMIDE COMPOUND
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Paragraph 0134-0137, (2020/10/08)
PROBLEM TO BE SOLVED: To provide a production method of an amide compound, which can use a variety of carboxylic acid halides and can produce a desired amide compound at a yield higher than a batch process by suppressing a side reaction. SOLUTION: Provided is a production method of an amide compound using a flow type reactor, in which the flow type reactor includes: a first flow path; a second flow path; a first mixing means provided at a confluent part of the first flow path and the second flow path; and a third flow path that is connected to the first mixing means and arranged on a down stream side of the first mixing means, the production method comprising: a mixing step of obtaining a mixed liquid by circulating a first liquid containing the carboxylic acid halide in the first flow path, circulating a second liquid containing an amine compound having a molecular weight of 1,000 or less, an inorganic alkali and water in the second flow path, and mixing the first liquid and the second liquid by the first mixing means to obtain a mixture; and a reaction step of obtaining an amide compound by circulating the mixed liquid in the third flow path and reacting the carboxylic acid halide and the amine compound in the third flow path. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2020,JPO&INPIT
