112108-86-8

Basic information

• Product Name: 4-Cyano-2-methylimidazole
• Synonyms: 4-Cyano-2-methylimidazole;2-METHYL-1H-IMIDAZOLE-4-CARBONITRILE(WXG00515)
• CAS NO: 112108-86-8
• Molecular Formula: C5H5N3
• Molecular Weight: 107.1133
• Mol File: 112108-86-8.mol

Chemical Properties

• Boiling Point: 384.4±15.0 °C(Predicted)
• Appearance: /
• Density: 1.21±0.1 g/cm3(Predicted)
• PKA: 9.73±0.10(Predicted)
• CAS DataBase Reference: 4-Cyano-2-methylimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Cyano-2-methylimidazole(112108-86-8)
• EPA Substance Registry System: 4-Cyano-2-methylimidazole(112108-86-8)

Safety Data

• Hazardous Substances Data: 112108-86-8(Hazardous Substances Data)

Upstream product

• 33468-67-6 2-methyl-4-(trifluoromethyl)-1H-imidazole 
• 1604818-05-4 1-trityl-2-methyl-1H-imidazole-4-carbonitrile 
• 35034-22-1 2-methylimidazole-4⁽⁵⁾-carbaldehyde 

Relevant articles and documents

HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS AND COMBINATIONS THEREOF

Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY

The invention relates to new bicyclic heterocycle compounds of formula (I): wherein R1 is seected from specific pyrazolyl, imidazolyl, pridinyl and triazolyl groups. The invention also realtes to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

LXR MODULATORS

The present invention provides compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as modulators of liver X receptors (LXR), compositions comprising any of such novel compounds, methods of using these compounds or compositions as medicaments for prevention or treatment of diseases or disorders related to liver X receptor (LXR), as well as methods of preparing these LXR modulators and using them in the manufacture of medicaments.

HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS

Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.