1135282-93-7 Usage
Description
1H-Pyrrole-2-carboxylic acid, 4-(1-oxopropyl)-, Methyl ester, also known as N-acetyl-L-proline methyl ester, is a chemical compound that features a pyrrole ring with a carboxylic acid functionality and a methyl ester group. It is recognized for its structural properties and reactivity, making it a valuable building block in the synthesis of pharmaceuticals and other organic compounds. Due to its potential applications in medicinal chemistry and drug development, it is essential to handle and store this compound with proper safety measures.
Uses
Used in Pharmaceutical Synthesis:
1H-Pyrrole-2-carboxylic acid, 4-(1-oxopropyl)-, Methyl ester is used as a building block for the synthesis of various pharmaceuticals and organic compounds. Its unique structure and reactivity contribute to the development of new drugs and therapeutic agents.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1H-Pyrrole-2-carboxylic acid, 4-(1-oxopropyl)-, Methyl ester serves as a key intermediate in the design and synthesis of novel compounds with potential therapeutic properties. Its structural features allow for the exploration of new chemical space and the discovery of innovative drug candidates.
Used in Drug Development:
1H-Pyrrole-2-carboxylic acid, 4-(1-oxopropyl)-, Methyl ester is utilized in drug development to create new molecules with specific biological activities. Its incorporation into drug candidates can lead to the enhancement of pharmacokinetic and pharmacodynamic properties, ultimately improving the efficacy and safety of new medications.
Used in Chemical Synthesis Industry:
1H-Pyrrole-2-carboxylic acid, 4-(1-oxopropyl)-, Methyl ester is used as a versatile reagent in the chemical synthesis industry. Its ability to participate in various chemical reactions makes it suitable for the production of a wide range of organic compounds for different applications, including but not limited to pharmaceuticals, agrochemicals, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 1135282-93-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,5,2,8 and 2 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1135282-93:
(9*1)+(8*1)+(7*3)+(6*5)+(5*2)+(4*8)+(3*2)+(2*9)+(1*3)=137
137 % 10 = 7
So 1135282-93-7 is a valid CAS Registry Number.
1135282-93-7Relevant articles and documents
PYRROLO[1,2-D][1,2,4]TRIAZINE-2-YL-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY
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Page/Page column 56, (2021/10/22)
The invention relates to novel compounds for use as inhibitors of NLRP3 inflammasone production, wherein such compounds are as defined by compounds of formula (I), Formula (I) and wherein the integers R1, R2 and R3 are defined in the description, and where the compounds may be useful as medicaments, for instance for use in the treatment of a disease or disorder that is associated with NLRP3 inflammasome activity.
Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control
Aronov, Alex M.,Qing, Tang,Martinez-Botella, Gabriel,Bemis, Guy W.,Cao, Jingrong,Chen, Guanjing,Ewing, Nigel P.,Ford, Pamella J.,Germann, Ursula A.,Green, Jeremy,Hale, Michael R.,Jacobs, Marc,Janetka, James W.,Maltais, Francois,Markland, William,Namchuk, Mark N.,Nanthakumar, Suganthini,Poondru, Srinivasu,Straub, Judy,Ter Haar, Ernst,Xiaoling, Xie
experimental part, p. 6362 - 6368 (2010/03/31)
The Ras/Raf/MEK/ERK signal transduction, an oncogenic pathway implicated in a variety of human cancers, is a key target in anticancer drug design. A novel series of pyrimidylpyrrole ERK inhibitors has been identified. Discovery of a conformational change
