1151665-78-9

Basic information

• Product Name: C₁₄H₂₀O₃
• Synonyms: C₁₄H₂₀O₃
• CAS NO: 1151665-78-9
• Molecular Weight: 236.311
• Mol File: 1151665-78-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₄H₂₀O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₂₀O₃(1151665-78-9)
• EPA Substance Registry System: C₁₄H₂₀O₃(1151665-78-9)

Safety Data

• Hazardous Substances Data: 1151665-78-9(Hazardous Substances Data)

Upstream product

• 75-64-9 tert-butylamine 
• 204254-96-6 (1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester 
• 1132659-99-4 (3R,4S,5R)-4-acetylamino-3-(1-ethyl-propoxy)-5-methanesulfonyloxy-cyclohex-1-enecarboxylic acid ethyl ester 

Relevant articles and documents

Method for preparing antiviral drug oseltamivir phosphate intermediate tert-butylamine derivative I

The invention discloses a method for preparing a tert-butylamine derivative, and relates to the field of drug synthesis. The method comprises the following steps: 1, preparing a magnesium-amine compound, namely, adding magnesium halide and tert-butylamine A into an aprotic solvent, and carrying out a mixing stirring reaction for 0.5-1.5 h at a temperature of 0-15 DEG C to prepare a mixed solutionA; 2, adding a compound B into the mixed solution A prepared in the step 1, and carrying out a stirring reaction for more than 8 hours to prepare a mixed solution B; and 3, supplementing tert-butylamine D into the mixed solution B prepared in the step 2, and carrying out a stirring reaction for 24-48h at a temperature of 50-70 DEG C to prepare a tert-butylamine derivative I. By controlling the preparation temperature of the compound, the addition mode of tert-butylamine and the time of the ring-opening reaction, the curing phenomenon in the reaction and the increase of by-products can be effectively controlled.