tert-Butylamine is manufactured by reacting isobutylamine
with sulfuric acid followed by cyanide to tert-butylformamide.
Hydrolysis yields t-butylamine. It is used as a solvent
and in organic syntheses.
Poison by ingestion.
Moderately toxic to humans by inhalation. A
corrosive liquid. See also n-BUTYLAMINE
and AMINES. Very dangerous fire hazard
when exposed to heat or flame. Very
exothermic reaction with 2,2-dibromo-l,3
dimethylcyclopropanoic acid. To fight fire,
use alcohol foam. When heated to
decomposition it emits toxic fumes of NOx.
Skin irritant. Flammable, dangerous fire
ChEBI: A primary aliphatic amine that is ethylamine substituted by two methyl groups at position 1.
Reactivity with Water No reaction; Reactivity with Common Materials: Liquid will attack some plastics; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Flush with water; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
UN1125 n-Butylamine, Hazard Class: 3; Labels:
3—Flammable liquid, 8—Corrosive material. UN2014
Isobutylamine, Hazard Class: 3; Labels: 3—Flammable
liquid, 8—Corrosive material
tert-Butylamine is a colorless liquid. It is used in the preparation of insecticides, pharmaceuticals, oil additives, and rubber accelerators.
Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fire.
Use a licensed professional
waste disposal service to dispose of this material. Dissolve
or mix the material with a combustible solvent and burn in
a chemical incinerator equipped with an afterburner andscrubber. All federal, state, and local environmental regulations must be observed.
A clear colorless liquid with an ammonia-like odor. Flash point 70°F. Less dense (at 6.2 lb / gal) than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion.
Alert: (n-isomer): Possible risk of
forming tumors, suspected of causing genetic defects, suspected reprotoxic hazard, Primary irritant (w/o allergic
reaction), (sec-isomer): Drug. n-Butylamine is used in
pharmaceuticals; dyestuffs, rubber, chemicals, emulsifying
agents; photography, desizing agents for textiles; pesticides, and synthetic agents. sec-Butylamine is used as a
fungistate. tert-Butylamine is used as a chemical intermediate in the production of tert-Butylaminoethyl methacrylate
(a lube oil additive); as an intermediate in the production
of rubber and in rust preventatives and emulsion deterrents
in petroleum products. It is used in the manufacture of
Inhalation causes irritation of nose, mouth, and lungs. Ingestion causes irritation of mouth and stomach. Contact with liquid causes severe irritation of eyes and moderate irritation of skin.
Air & Water Reactions
Highly flammable. May be sensitive to air . Soluble in water.
Butyl amines are highly flammable, colorless
liquids (n-turns yellow on standing) with ammoniacal or fishlike odors. n-isomer:
tert-Butylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides. Undergoes highly exothermic reaction with 2,2-dibromo-1,3-dimethylcyclopropanoic acid [J. Chem. Soc., 1, 1979, 2324].
Dry it with KOH or LiAlH4, and/or distil it from CaH2 or BaO. [Beilstein 4 IV 657.]
Intermediate for rubber accelerators, insecti-
cides, fungicides, dyestuffs, pharmaceuticals.
May form explosive mixture with air.
May accumulate static electrical charges, and may causeignition of its vapors. n-Butylamine is a weak base; reacts
with strong oxidizers and acids, causing fire and explosion
hazard. Incompatible with organic anhydrides; isocyanates,
vinyl acetate; acrylates, substituted allyls; alkylene oxides;
epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks some metals in
presence of moisture. The tert-isomer will attack some
forms of plastics