116408-80-1Relevant articles and documents
Total synthesis of coriandrin and 7-demethylcoriandrin via a new synthesis of isocoumarins
Mal, Dipakranjan,Bandyopadhyay, Mousumi,Ghorai, Sujit K.,Datta, Kalyani
, p. 3677 - 3680 (2000)
Indenone epoxides 8, prepared from the corresponding indenones, have been shown to undergo clean thermal rearrangement to give isocoumarins 10 in high yields. This synthesis of isocoumarins, when applied to oxaindace-none 7, resulted in the total synthesis of coriandrin (1). (C) 2000 Elsevier Science Ltd.
Total Synthesis of Coriandrin
Kraus, George A.,Ridgeway, James
, p. 4735 - 4737 (1994)
Coriandrin, an antiviral agent, has been synthesized in nine steps from diketone 3.The key steps in the synthesis include an efficient aromatization reaction using N-bromosuccinimide and a palladium-mediated coupling of a benzylic bromide with a vinyl stannane.
