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(R)-2-Benzyloxy-1,3-propanediol 1-(p-toluenesulfonate) is a chemical compound that features a propanediol molecule with a benzyloxy group attached to one of the carbon atoms and a p-toluenesulfonate group. (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1(P-TOLUENESULFONATE) is known for its versatile reactivity and ability to participate in a range of chemical transformations, making it a valuable asset in organic chemistry.

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  • 119870-20-1 Structure
  • Basic information

    1. Product Name: (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE)
    2. Synonyms: (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE);2-benzyloxy-1,3-propanediol 1-(toluene-4-sulfonate);2-Benzyl-sn-glycerol 3-tosylate, (R)-2-Benzyloxy-3-(p-toluenesulfonyloxy)-1-propanol;(R)-2-Benzyloxy-3-(p-toluenesulfonyloxy)-1-propanol;2-Benzyl-sn-glycerol 3-tosylate
    3. CAS NO:119870-20-1
    4. Molecular Formula: C17H20O5S
    5. Molecular Weight: 336.4027
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 119870-20-1.mol
  • Chemical Properties

    1. Melting Point: 40-43 °C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE)(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE)(119870-20-1)
    11. EPA Substance Registry System: (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE)(119870-20-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: 22-24/25
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 119870-20-1(Hazardous Substances Data)

119870-20-1 Usage

Uses

Used in Pharmaceutical Synthesis:
(R)-2-Benzyloxy-1,3-propanediol 1-(p-toluenesulfonate) is used as a reagent in the synthesis of pharmaceuticals, leveraging its versatile reactivity and ability to undergo various chemical transformations. The p-toluenesulfonate group acts as a leaving group in substitution or elimination reactions, facilitating the creation of new compounds with potential medicinal properties.
Used in Organic Chemistry:
In the field of organic chemistry, (R)-2-Benzyloxy-1,3-propanediol 1-(p-toluenesulfonate) serves as a valuable reagent for conducting a wide array of chemical reactions. Its unique structure allows it to participate in numerous chemical transformations, contributing to the development of novel organic compounds.
Used as a Chiral Building Block:
(R)-2-Benzyloxy-1,3-propanediol 1-(p-toluenesulfonate) is also utilized as a chiral building block in the construction of complex molecules with specific stereochemistry. Its enantiomeric purity is crucial for the synthesis of biologically active compounds, as the stereochemistry of a molecule can significantly influence its biological activity and interactions with target molecules.
Used in Chemical Research:
(R)-2-BENZYLOXY-1,3-PROPANEDIOL 1(P-TOLUENESULFONATE) is employed in chemical research to explore new reaction pathways, develop innovative synthetic methods, and create novel molecules with potential applications in various industries, including pharmaceuticals, materials science, and agrochemicals. Its unique structure and reactivity make it an attractive candidate for studying new chemical phenomena and advancing the field of organic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 119870-20-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,8,7 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 119870-20:
(8*1)+(7*1)+(6*9)+(5*8)+(4*7)+(3*0)+(2*2)+(1*0)=141
141 % 10 = 1
So 119870-20-1 is a valid CAS Registry Number.

119870-20-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-(-)-3-tosyloxy-2-benzyloxy-1-propanol

1.2 Other means of identification

Product number -
Other names (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1-(P-TOLUENESULFONATE)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:119870-20-1 SDS

119870-20-1Relevant articles and documents

Synthesis of optically active lipopeptide analogs from the outer membrane of Escherichia coli

Kurimura,Takemoto,Achiwa

, p. 2590 - 2596 (2007/10/02)

The synthesis of optically active lipopeptide derivatives has been accomplished by the use of chiral glycerol derivatives. Lipopeptide derivatives with (R)-glycerol moieties showed higher mitogenic activities than those with the (S)-configuration. N-2,2,2-Trichloroethoxycarbonyl lipopeptide derivatives increased mitogenic activity.

New synthesis of 2-thio-PAF and related compounds as substrates of PAF acetylhydrolase and phospholipase A2

Murata,Ikoma,Achiwa

, p. 1335 - 1336 (2007/10/02)

2-Thio PAF and related compounds (1 a-c) as substrates of PAF acetylhydrolase and phospholipase A2 were synthesized stereoselectively from optically active 2-O-benzylglycerol monoacetate.

Synthesis of biologically active acycloazt derivatives and related compounds

Murata,Achiwa

, p. 836 - 838 (2007/10/02)

The synthesis of optically active acyclic analogues of 3'-azido-3'-deoxythymidine, which lack only the 2'-CH2 of the sugar, is described. The synthesis of some nucleoside analogues that contain the N-acetyl-D-neuraminic acid moiety is also described.

HIGHLY EFFICIENT LIPASE-CATALYZED ASYMMETRIC SYNTHESIS OF CHIRAL GLYCEROL DERIVATIVES LEADING TO PRACTICAL SYNTHESIS OF (S)-PROPRANOLOL

Terao, Yoshiyasu,Murata, Masakazu,Achiwa, Kazuo,Nishio, Toshiyuki,Akamtsu, Minoru,Kamimura, Minoru

, p. 5173 - 5176 (2007/10/02)

Efficient asymmetric synthesis of chiral glycerol derivatives was realized by lipase-catalyzed reaction in organic medium and its application for synthesis of (S)-propranolol was demostrated.

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