128223-59-6

Upstream product

• 109429-01-8 (S)-2-(benzyloxy)-3-hydroxypropyl acetate 
• 98-59-9 p-toluenesulfonyl chloride 
• 14690-00-7 2-O-benzylglycerol 

Downstream Products

• 119870-22-3 (S)-2-benzyloxy-3-isopropylamino-1-propanol 
• 119870-21-2 ((S)-2-Benzyloxy-3-chloro-propyl)-isopropyl-amine 
• 146797-75-3 (R)-2-O-benzyl-3-O-tetrahydropyranyl-1-O-tosylglycerol 
• 146923-48-0 (S)-2-O-benzyl-3-O-hexadecyl-1-O-tetrahydropyranylglycerol 
• 41274-09-3 (R)-3-tosyloxy-1,2-propanediol 
• 119870-20-1 (R)-(-)-3-tosyloxy-2-benzyloxy-1-propanol 

Relevant academic research and scientific papers

Synthesis of optically active lipopeptide analogs from the outer membrane of Escherichia coli

The synthesis of optically active lipopeptide derivatives has been accomplished by the use of chiral glycerol derivatives. Lipopeptide derivatives with (R)-glycerol moieties showed higher mitogenic activities than those with the (S)-configuration. N-2,2,2-Trichloroethoxycarbonyl lipopeptide derivatives increased mitogenic activity.

New synthesis of 2-thio-PAF and related compounds as substrates of PAF acetylhydrolase and phospholipase A2

2-Thio PAF and related compounds (1 a-c) as substrates of PAF acetylhydrolase and phospholipase A2 were synthesized stereoselectively from optically active 2-O-benzylglycerol monoacetate.

HIGHLY EFFICIENT LIPASE-CATALYZED ASYMMETRIC SYNTHESIS OF CHIRAL GLYCEROL DERIVATIVES LEADING TO PRACTICAL SYNTHESIS OF (S)-PROPRANOLOL

Efficient asymmetric synthesis of chiral glycerol derivatives was realized by lipase-catalyzed reaction in organic medium and its application for synthesis of (S)-propranolol was demostrated.