128223-59-6Relevant articles and documents
Synthesis of optically active lipopeptide analogs from the outer membrane of Escherichia coli
Kurimura,Takemoto,Achiwa
, p. 2590 - 2596 (2007/10/02)
The synthesis of optically active lipopeptide derivatives has been accomplished by the use of chiral glycerol derivatives. Lipopeptide derivatives with (R)-glycerol moieties showed higher mitogenic activities than those with the (S)-configuration. N-2,2,2-Trichloroethoxycarbonyl lipopeptide derivatives increased mitogenic activity.
HIGHLY EFFICIENT LIPASE-CATALYZED ASYMMETRIC SYNTHESIS OF CHIRAL GLYCEROL DERIVATIVES LEADING TO PRACTICAL SYNTHESIS OF (S)-PROPRANOLOL
Terao, Yoshiyasu,Murata, Masakazu,Achiwa, Kazuo,Nishio, Toshiyuki,Akamtsu, Minoru,Kamimura, Minoru
, p. 5173 - 5176 (2007/10/02)
Efficient asymmetric synthesis of chiral glycerol derivatives was realized by lipase-catalyzed reaction in organic medium and its application for synthesis of (S)-propranolol was demostrated.