120-70-7Relevant articles and documents
Selective dopamine chemosensing using silver-enhanced fluorescence
Ganguly, Mainak,Mondal, Chanchal,Jana, Jayasmita,Pal, Anjali,Pal, Tarasankar
, p. 4120 - 4128 (2014)
Condensation product of salicylaldehyde and 1,3 propylenediamine becomes a diiminic Schiff base, which is oxidized by AgNO3 in alkaline solution, and in turn, stable Ag(0) is produced at room temperature. Under this condition, the solution exhibits intense silver nanoparticle enhanced fluorescence (SEF) with the em at 412 nm. Dopamine is selectively detected down to the nanomolar level via exclusive fluorescence quenching of the SEF. Dopamine-infested solution regains the fluorescence [i.e., SEF in the presence of Hg(II) ions]. Thus dopamine and Hg(II) in succession demonstrate "turn off/on" fluorescence due to the change in the scattering cross section of Ag(0) and gives a quantitative measure of dopamine in real samples. The proposed method is free from interferences of common biocompetitors.
Synthesis and in vitro antioxidant evaluation of new bis(α-aminoalkyl)phosphinic acid derivatives
Sarac, Kamiran,Orek, Cahit,Cetin, Ahmet,Dastan, Taner,Koparir, Pelin,Dastan, Sevgi Durna,Koparir, Metin
, p. 1284 - 1289 (2016)
Diamines were added to arylaldehydes in ethanol, which resulted in corresponding diimines. Novel bis-1-aminophosphinic acid compounds were synthesized through the interaction of diimines and hypophosphorous acid. The new compounds were characterized by elemental analyses, FT-IR and1H,13C and31P NMR techniques. The in vitro antioxidant activity of the newly synthesized compounds were measured and found to exhibit significantly higher antioxidant activity than the standard.
Hetero-metallic trinuclear nickel(II)-cadmium(II) complexes of a salicylaldimine ligand with thiocyanate, cyanate and azide ions: Isolation of a pair of polymorphs with thiocyanate ion
Das, Lakshmi Kanta,Drew, Michael G.B.,Ghosh, Ashutosh
, p. 247 - 254 (2013)
Four new trinuclear hetero-metallic nickel(II)-cadmium(II) complexes [(NiL)2Cd(NCS)2] (1A and 1B), [(NiL)2Cd(NCO) 2] (2) and [(NiL)2Cd(N3)2] (3) have been synthesized using [NiL] as a so-called "ligand complex" (where H2L = N,N′-bis(salicylidene)-1,3-propanediamine) and structurally characterized. Crystal structure analyses reveal that all four complexes contain a trinuclear moiety in which two square planar [NiL] units are bonded to a central cadmium(II) ion through double phenoxido bridges. The Cd(II) is in a six-coordinate distorted octahedral environment being bonded additionally to two mutually cis nitrogen atoms of terminal thiocyanate (in 1A and 1B), cyanate (in 2) and azide (in 3). Complexes 1A and 1B have the same molecular formula but crystallize in very different monoclinic unit cells and can be considered as polymorphs. On the other hand, the two isoelectronic complexes 2 and 3 are indeed isomorphous and crystallize only in one form. Their conformation is similar to that observed in 1A.
Preparation and structural characterization of hetero-dinuclear Schiff base copper(II)-zinc(II) complexes and their inhibition studies on Helicobacter pylori urease
You, Zhong-Lu,Lu, Yao,Zhang, Na,Ding, Bo-Wen,Sun, Hui,Hou, Peng,Wang, Che
, p. 2186 - 2194 (2011)
A series of hetero-dinuclear CuII-ZnII complexes, [CuZnCl2L1] (1), [CuZnCl2L2] (2), [CuZnBr2L3] (3), [CuZnBr2L4(DMF)] (4), [CuZnCl2L4] (5), [CuZnCl2L5] (6), [CuZnCl2L3] (7) and [CuZnBr2L1] (8), where L1, L2, L3, L4 and L5 are the deprotonated forms of N,N′-bis(3-ethoxysalicylidene) -1,3-propanediamine (H2L1), N,N′-bis(2- hydroxynaphthylmethylidene)-1,3-propanediamine (H2L2), N,N′-bis(3-methoxysalicylidene)-1,3-propanediamine (H2L 3), N,N′-bis(salicylidene)-1,3-propanediamine (H 2L4) and N,N′-bis(salicylidene)-1,4-butanediamine (H2L5), respectively, have been synthesized and characterized by physico-chemical methods and single-crystal X-ray diffraction. The complexes were tested for their urease inhibitory activity. Complexes 1 and 8 show effective urease inhibitory activity with IC50 values of 2.2 and 10.7 μM. The molecular docking study of the complexes with the Helicobacter pylori urease was performed.
The impact of anion-modulated structural variations on the magnetic coupling in trinuclear heterometallic CuII-CoII complexes derived from a salen-type Schiff base ligand
Ghosh, Soumavo,Aromí, Guillem,Gamez, Patrick,Ghosh, Ashutosh
, p. 3341 - 3349 (2014)
Three new trinuclear heterometallic [(CuIIL)2Co IIX2] complexes [H2L = N,N′- bis(salicylidene)-1,3-propanediamine and X = thiocyanate (1), benzoate (2), or azide (3)] have been synthesized by reacting the metalloligand [CuL] with Co(ClO4)2·6H2O and the NH 4+ or Na+ salt of the corresponding anion in methanol. Structural characterization reveals that the central CoII ion is connected to two terminal metalloligands through μ1,1- diphenoxido bridges in all three complexes. However, two monodentate thiocyanato ions, which are mutually cis coordinated to the Co atom in 1, generate a "bent" structure, whereas the trans-coordinated syn-syn bridging benzoato (1κO:2κO′) and the end-on bridging azido (μ1,1) coligands in 2 and 3, respectively, produce linear structures. The changes in the number and nature of the bridges with a shortening of the distances between the metal centers leads to a concomitant decrease of the average CuII-O-CoII bridging angle from 99.3(2) to 97.1(4) and 91.5(1)° for 1, 2 and 3, respectively. Variable-temperature magnetic susceptibility measurements show the presence of a dominant antiferromagnetic coupling between the Cu-Co pairs in all three complexes. However, a steady decrease of the magnitude of the exchange coupling constant (JCu-Co) is observed from -33.4 (for 1) to -11.4 (for 2) and -2.15 cm-1 (for 3). This trend suggests that larger Cu-O-Co angles are associated with stronger antiferromagnetic coupling. Anion-mediated geometrical variations generate three heterometallic complexes with distinct trinuclear Cu2Co cores as a result of different diphenoxido bridging angles between the CuII and CoII ions. Magnetic studies reveal decreased antiferromagnetic exchange interactions associated with a decrease of this bridging angle. Copyright
Antiferro- to ferromagnetic crossover in diphenoxido bridged NiII2MnII complexes derived from N2O2 donor Schiff base ligands
Seth, Piya,Figuerola, Albert,Jover, Jesús,Ruiz, Eliseo,Ghosh, Ashutosh
, p. 57 - 63 (2016)
Three new trinuclear NiII-MnII complexes have been synthesized using three different "metalloligands" [NiL1], [NiL2] and [NiL3] derived from the Schiff bases H2L1 = N,N′-bis(salicylidene)-1,3-pentanediamine, H2L2 = N,N′-bis(salicylidene)-1,3-propanediamine and H2L3 = N,N′-bis(salicylidene)-1,3,-diaminopropan-2-ol), respectively. In all three complexes, [(NiL1)2Mn(OOCPh)2(H2O)2]·CH3OH (1), [(NiL2)2Mn(OOCPh)2(CH3OH)2]·CH3OH (2) and [(NiL3)2Mn(OOCPh)2(H2O)2]·CH3OH (3), in addition to the double phenoxido bridge, the two terminal NiII atoms are linked to the central MnII by means of a syn-syn bridging benzoate, giving rise to a linear structure. Complex 1 with Ni-O-Mn angle of 97.35° exhibits antiferromagnetic interactions (JNi-Mn = -0.60 cm-1) whereas ferromagnetic exchange is observed in 2 and 3 (JNi-Mn = +2.00 and +1.10 cm-1 respectively) having Ni-O-Mn angle 97.34° (in 2), 97.27° (in 3). Theoretical calculations have been performed in order to understand the effect of structural parameters that can tune the magnetic properties of this type of complexes such as small differences in the Ni-O-Mn angle and/or slight variations in intermolecular contacts within the crystal.
Structure and spin-spin interactions in a linear trinuclear Ni(II) complex
Elmali, Ayhan,Elerman, Yalcin,Svoboda, Ingrid,Fuess, Hartmut,Griesar, Klaus,Haase, Wolfgang
, p. 665 - 670 (1996)
[Ni3(C2H3O2)2(C 3H8NO)2L2] [(L=N,N'-1,3-propyl-disalicylaldimine), (C2H3O2)=acetate, (C3H8NO)=hydroxymethyl-dimethylamine] has been synthesized and ils crystal structure determined, [C44H54N6O10Ni3], triclinic, space group P1?, a = 9.560(1), b = 10.681(1), c = 12.200(1) ?, α = 112.17(1), β = 101.25(1), γ = 90.32(1)°, V = 1127.3 ?3 Z = 1. The molecule is linearly trinuclear with octahedral coordination of each nickel ion. The Ni-Ni distance is 3.048(1) ?. Each nickel(II) atom is in an octahedral coordination. Magnetic susceptibility measurements in the range 4.2 1 = -2.2 cm-1) and between the terminal Ni atoms (J2 = -1.7 cm-1).
An investigation of some Schiff base derivatives as chemosensors for Zn(II): The performance characteristics and potential applications
Ergun, Ece,Ergun, ümit,?leri, ?zgür,Kü?ükmüzevir, Muhammed Fatih
, p. 273 - 286 (2018)
The fluorescence properties of four simple Schiff bases (LH2, LDMH2, LH2 H and LDMHH2) and their potential application as chemosensors for the detection of zinc ion in aqueous solution have been investigated. While LH2 and LDMH2 have displayed specific recognition to Zn(II), the reduced derivatives (LH2 H and LDMHH2) of these ligands have shown no fluorescence response due to the lack of C[dbnd]N group. The Job plots, fluorescence titration experiments and ESI-MS results indicate the formation of 1:1 complexes between sensors and Zn(II). The analytic methods based on LH2 and LDMH2 as chemosensors have been proposed and optimized to detect Zn(II) ions in aqueous solution. The optimized methods have shown a good range of linearity, high precision, good accuracy and low detection limit. As an alternative to these methods, LH2 and LDMH2 have the capability to detect Zn(II) ions by naked eye under UV lamp. Moreover, LH2-Zn and LDMH2-Zn complexes have the ability to be a staining agent for identifying the radiation treatment of food by DNA comet assay.
Rare trinuclear NiII2MII complexes (MII?=?Mn, Fe and Co) with a reduced Schiff base ligand: Synthesis, structures and magnetic properties
Hazari, Alokesh,Ghosh, Tanmoy Kumar,Gómez-García, Carlos J.,Ghosh, Ashutosh
, p. 168 - 175 (2018)
Three new trinuclear hetero-metallic NiII2MII complexes with MII = Mn, Fe and Co have been synthesized using a [NiLR] “metalloligand”, where H2LR = N,N′-bis(2-hydroxybenzyl)-1,3-propanediamine. All complexes have been characterized by elemental analysis, spectroscopic methods, single crystal XRD and magnetic and electrochemical studies. In the three complexes, in addition to the double phenoxido bridges, the two terminal NiII atoms are linked to the central MII [M = Mn(1), Fe(2) and Co(3)] ion by means of a bridging carboxylato co-anion, giving rise to a linear NiII-MII-NiII structure. Variable temperature magnetic susceptibility measurements show the presence of weak ferromagnetic and antiferromagnetic exchange interactions mediated through the double phenoxido bridges with J values of +8.5 and ?3.0 cm?1 for complexes 1 and 2, respectively. Compound 3 shows the presence of antiferromagnetic interactions. Cyclic voltammetry shows a common quasi-reversible one electron oxidation corresponding to the Ni(II)/Ni(III) process in 1–3 and an irreversible M(II)/M(III) oxidation for Mn(1) and Fe(2).
Kinetics and mechanism of the ligand exchange reaction between tetradentate schiff base N,N'-ethylen-bis (salicylaldimine) and Ni(N,N'-propylen-bis(salicylaldimine))
Vafazadeh, Rasoul,Bagheri, Maryam
, p. 21 - 26 (2015)
Visible spectrophotometry is used to study the kinetics of ligand exchange in the system Ni(salpn)/H2salen with or without triethylamine (NEt3) and H2O in dimethylformamide (DMF) solvent at 25 ± 0.1 °C and 0.01MNaNO3 [H2salen and H2salpn are N,N'-ethylen-bis(salicylaldimine) and N,N'-propylen-bis(salicylaldimine), respectively]. It was found that the reaction rate is of the first-order with respect to Ni(salpn). In addition, the effect of NEt3 andH2Oon the rate of the reaction was examined. The rate of the ligand exchange reaction was accelerated by adding NEt3 to the reaction mixture. However, the ligand exchange rate was not changed by adding H2O to the mixture reaction. The effects of NEt3 and H2O on the ligand exchange rate show that deprotonation/protonation of the H2salen ligand and anionic form of H2salen is important. On the basis of these results, the reaction mechanism is discussed.
