1201645-42-2

Basic information

• Product Name: 2-(4-(8-(9H-carbazol-2-yl)-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile
• Synonyms: 2-(4-(8-(9H-carbazol-2-yl)-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile
• CAS NO: 1201645-42-2
• Molecular Weight: 477.568
• Mol File: 1201645-42-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-(8-(9H-carbazol-2-yl)-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-(8-(9H-carbazol-2-yl)-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile(1201645-42-2)
• EPA Substance Registry System: 2-(4-(8-(9H-carbazol-2-yl)-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile(1201645-42-2)

Safety Data

• Hazardous Substances Data: 1201645-42-2(Hazardous Substances Data)

Upstream product

• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 96546-77-9 N-tosyl-5-bromoindole 
• 40119-34-4 2-methyl-2-(4-methylphenyl)propionitrile 
• 853908-50-6 6-bromo-3-nitroquinolin-4-ol 
• 1201643-79-9 2-(4-((5-bromo-1-tosyl-1H-indol-3-yl)(hydroxy)methyl)phenyl)-2-methylpropanenitrile 
• 1201643-78-8 2-(4-(5-bromo-1-tosyl-1H-indol-3-carbonyl)phenyl)-2-methylpropanenitrile 
• 1201643-80-2 2-(4-((5-bromo-1-tosyl-1H-indol-3-yl)methyl)phenyl)-2-methylpropanenitrile 
• 1201643-76-6 2-(4-((6-bromo-3-nitroquinolin-4-yl)(phenylthio)methyl)phenyl)-2-methylpropanenitrile 
• 1201643-72-2 2-(4-(3-acetyl-8-bromo-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile 
• 1201643-84-6 (E)-2-(4-(2-(5-bromo-2-(2-nitroethylideneamino)phenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile 
• 1201643-85-7 2-(4-((6-bromo-3-nitroquinolin-4-yl)methyl)phenyl)-2-methylpropanenitrile 
• 1201643-77-7 2-(4-((3-amino-6-bromoquinolin-4-yl)methyl)phenyl)-2-methylpropanenitrile 
• 1201643-82-4 N-(4-bromo-2-(2-(4-(2-cyanopropan-2-yl)phenyl)acetyl)phenyl)formamide 
• 1201643-83-5 2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile 

Relevant articles and documents

PHOSPHATIDYLINOSITOL 3 KINASE INHIBITORS

Provided are compounds according to Formula (I), or stereoisomer, prodrug, polymorph, or pharmaceutically acceptable salt forms thereof, wherein X, Y, R1, R6 , R7, and R8 are as defined, which compounds are effective inhibitors of PI3-kinase and/or other medically and clinically relevant kinases. Also provided are pharmaceutical compositions and methods of using the compounds and compositions as PB -kinase and kinase inhibitors. More particularly, the compounds of the invention provide treatments and therapeutics for human diseases regulated by, or associated with, the activity of, PI3-kinases and/or protein kinases, or mutant or variant forms thereof.