121805-97-8Relevant articles and documents
Alkylation of 2-acetylpyrrole and 1-alkyl-2-acetylpyrroles under solid/liquid phase-transfer conditions
Goldberg Yu.,Abele,Shymanska
, p. 557 - 562 (1991)
The alkylation of 2-acetylpyrrole with alkyl iodides in the benzene/solid KOH system in the presence of 18-crown-6 at room temperature gives the corresponding 1-alkyl derivatives in high yields. The phase-transfer catalysed alkylation of 1-alkyl-2-acetylpyrroles without solvent leads to side-chain di-C-alkylated products, i.e. ketones of the (1-alkyl-2-pyrrolyl)COCHR2 type in satisfactory yields.
Catalyst-free hydrogenation of alkenes and alkynes with hydrazine in the presence of oxygen
Menges, Nurettin,Balci, Metin
, p. 671 - 676 (2014/04/03)
A series of alkenes and alkynes was subjected to reduction with hydrazine hydrate in ethanol in the presence of oxygen. An efficient method was developed for the reduction of C-C double bonds and C-C triple bonds with diimide, generated in situ from hydrazine hydrate by oxidation with oxygen. The reduction process proceeded for 24-48? hours with high chemoselectivity and excellent yields. This reduction procedure offers synthetic advantages over metal-catalyzed hydrogenation as well as other systems. Georg Thieme Verlag Stuttgart New York.
N-(lower alkyl)-2-(3'ureidobenzyl)pyrrolidines
-
, (2008/06/13)
N-(lower alkyl)-2-(3'-ureidobenzyl)pyrrolidines and N-(lower alkyl)-2-(3'-ureidobenzyl)-5-(lower alkyl)pyrrolidines are useful for lowering intraocular pressure in mammals, for example, in the treatment of glaucoma.
