1239450-42-0

Basic information

• Product Name: 2-benzaMido-3-Methoxy-3-oxopropyl benzoate
• Synonyms: 2-benzaMido-3-Methoxy-3-oxopropyl benzoate
• CAS NO: 1239450-42-0
• Molecular Formula: C18H17NO5
• Molecular Weight: 327.33128
• EINECS: -0
• Mol File: 1239450-42-0.mol

Chemical Properties

• Boiling Point: 548.9±45.0 °C(Predicted)
• Appearance: /
• Density: 1.233±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.42±0.46(Predicted)
• CAS DataBase Reference: 2-benzaMido-3-Methoxy-3-oxopropyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzaMido-3-Methoxy-3-oxopropyl benzoate(1239450-42-0)
• EPA Substance Registry System: 2-benzaMido-3-Methoxy-3-oxopropyl benzoate(1239450-42-0)

Safety Data

• Hazardous Substances Data: 1239450-42-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
2-benzaMido-3-Methoxy-3-oxopropyl benzoate is employed as a chemical intermediate for the synthesis of various pharmaceuticals, leveraging its potential pharmacological properties to contribute to the development of new drugs.
Used in Anti-inflammatory Applications:
In the medical field, 2-benzaMido-3-Methoxy-3-oxopropyl benzoate is used as an anti-inflammatory agent, potentially aiding in the reduction of inflammation and associated symptoms, thus benefiting patients with inflammatory conditions.
Used in Analgesic Formulations:
2-benzaMido-3-Methoxy-3-oxopropyl benzoate is utilized as an analgesic, helping to alleviate pain due to its capacity to interact with pain receptors and pathways, providing relief in various painful conditions.
Used in Antipyretic Medications:
2-benzaMido-3-Methoxy-3-oxopropyl benzoate is used as an antipyretic to reduce fever, making it a component in medications aimed at lowering elevated body temperatures.
Used in Antioxidant Formulations:
Given its antioxidant properties, 2-benzaMido-3-Methoxy-3-oxopropyl benzoate is used in formulations designed to combat oxidative stress, which can be beneficial in the prevention and treatment of various diseases associated with oxidative damage.
Used in Antimicrobial Agents:
2-benzaMido-3-Methoxy-3-oxopropyl benzoate is also used as an antimicrobial agent, contributing to the fight against infections by inhibiting the growth of microorganisms, thus playing a role in various sanitizing and medicinal products.
Used in Cosmetics Industry:
2-benzaMido-3-Methoxy-3-oxopropyl benzoate may be utilized in the cosmetics industry for its potential benefits in skincare products, such as anti-aging and anti-inflammatory properties, enhancing the efficacy of cosmetic formulations.
Used in Agricultural Applications:
In agriculture, this compound could be employed for its antimicrobial properties to protect crops from diseases and pests, thereby contributing to increased crop yields and quality.

Upstream product

• 5619-04-5 methyl 2-amino-3-hydroxypropanoate hydrochloride 
• 98-88-4 benzoyl chloride 
• 903566-73-4 [1S,2S,6S,7S]-1,6-diaza-4,9-dioxa-2,7-dimethoxycarbonylbicyclo[4.4.1]undecane 
• 2788-84-3 (S)-serine methyl ester 

Downstream Products

• 81077-03-4 methyl benzoyloxy-α-diazopropionate 

Relevant articles and documents

Efficient preparation of 2,4-methanoproline

Using a modification of the route described by Clardy and Hughes et al., 2,4-methanoproline hydrochloride (1) was prepared in four steps and 70% overall yield from DL-serine methyl ester.

Synthesizing method using serine to prepare Ramipril key intermediate

The invention relates to a synthesizing method using serine to prepare a Ramipril key intermediate. The Ramipril key intermediate is 2-azabicyclo[3.3.0] octane-3-carboxylic acid hydrochloride or benzyl ester hydrochloride. The synthesizing method includes: using the serine as the initial raw material, and sequentially performing esterification, acyl chloride acylation, deacidification, Michael addition, hydrolysis and hydrogenation reduction to obtain the Ramipril key intermediate. The synthesizing method has the advantages that the key intermediate is synthesized by a five-step method, and the synthesizing method is cheap in raw material, environmentally friendly, simple in preparation process, simple to operate, mild in reaction condition, short in reaction cycle, convenient in post-treatment, low in equipment requirement, capable of avoiding heavy metal pollution and the use of expensive catalysts, few in three wastes, high in product yield and purity and suitable for industrial production.

Conversion of isomeric 2:3 adducts (aminoacid-formaldehyde) to N-acyl-pseudoprolines derivatives

Reaction of acyl chlorides or acid anhydrides with isomeric 2:3 adducts derived from condensation of l-serine (1a), l-threonine (1b) and l-cysteine (1c) methyl esters with formaldehyde afforded N-acyl-pseudoprolines 7-19 in various yields. These 2:3 adducts can be considered as synthetic equivalents of oxaproline and thiaproline moieties. The present work revealed the versatile behaviour of the two 2:3 adducts as a consequence of the ring-chain tautomerism occurring in the five- and/or seven-membered rings.

New synthesis of 7-azabicyclo[2.2.1]heptane-1-carboxylic acid

This report describes a new synthetic route to 7-azabicyclo[2.2.1]heptane-1-carboxylic acid (Ahc), a constrained proline analogue, in which the key step is the Diels-Alder reaction using methyl 2-benzamidoacrylate as dienophile.