124211-79-6Relevant articles and documents
One-pot synthesis of new imidazo[1,2-a]pyridine and midazo[1,2-a]pyrimidine derivatives
Georgescu, Florentina,Georgescu, Emilian,Drǎghici, Constantin,Iuhas, Paula C.,Filip, Petru I.
, p. 349 - 352 (2007/10/03)
New imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives were easily obtained by an one-pot synthesis that implies the reaction of the corresponding 2-aminoheterocycles with N,N-dimethylformamide dimethylacetal (DMFDMA), followed by the reactio
The transformations of 4-heteroarylaminomethylene-5(4H)-oxazolones into dehydropeptide derivatives
Aljaz-Rozic,Svete,Stanovnik
, p. 1605 - 1611 (2007/10/03)
2-Phenyl-4-heteroarylaminomethylene-5(4H)-oxazolones 3, which were prepared from the corresponding N,N-dimethyl-N'-heteroarylformamidines 1 and hippuric acid 2 in acetic anhydride, react with amino acids giving dehydropeptide derivatives 4, 5, and 6 as products. Dehydration of N-protected peptides 7-10, containing glycine at the C-terminal, followed by the reaction with formamidines 1 gave 2-substituted-4-heteroarylaminomethylene-5(4H)-oxazolones 11-14.
Reactions of N-Heteroarylformamide Oximes and N-Heteroarylacetamide Oximes with N,N-Dimethylformamide Dimethyl Acetal. Synthesis of 2-Methyl-s-triazoloazines and N-Methylcyanoaminoazines
Stanovnik, Branko,Stimac, Anton,Tisler, Miha,Vercek, Bojan
, p. 577 - 583 (2007/10/02)
N-Heteroarylformamide oximes 3 (R = H) were converted with N,N-dimethylformamide dimethyl acetal (DMFDMA) into N-heteroaryl-N-methylcyanoamino compounds 5, as the main products.In some instances N-heteroarylcyanoamino compounds 4, cyanoimino compounds 7, and some other products, such as 9 and 10 were also formed.On the other hand, N-heteroarylacetamide oximes 3 (R = CH3) were cyclized under the same reaction conditions into 2-methyl-s-triazoloazines (6).N-Heteroarylacetamide O-methyl oximes 11 and 12 were prepared from the corresponding acetamidines 2 (R = CH3) and O-methylhydroxylamine.
