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CAS

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1252762-31-4

tert-butyl (R)-4-(4-chloro-3-hydroxyphenyl)-2-oxopyrrolidine-1-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1252762-31-4 Structure

  • Basic information

    1. Product Name: tert-butyl (R)-4-(4-chloro-3-hydroxyphenyl)-2-oxopyrrolidine-1-carboxylate
    2. Synonyms: tert-butyl (R)-4-(4-chloro-3-hydroxyphenyl)-2-oxopyrrolidine-1-carboxylate
    3. CAS NO:1252762-31-4
    4. Molecular Formula:
    5. Molecular Weight: 311.765
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1252762-31-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: tert-butyl (R)-4-(4-chloro-3-hydroxyphenyl)-2-oxopyrrolidine-1-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: tert-butyl (R)-4-(4-chloro-3-hydroxyphenyl)-2-oxopyrrolidine-1-carboxylate(1252762-31-4)
    11. EPA Substance Registry System: tert-butyl (R)-4-(4-chloro-3-hydroxyphenyl)-2-oxopyrrolidine-1-carboxylate(1252762-31-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1252762-31-4(Hazardous Substances Data)

1252762-31-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1252762-31-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,2,7,6 and 2 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1252762-31:
(9*1)+(8*2)+(7*5)+(6*2)+(5*7)+(4*6)+(3*2)+(2*3)+(1*1)=144
144 % 10 = 4
So 1252762-31-4 is a valid CAS Registry Number.

1252762-31-4Relevant articles and documents

Synthesis and Evaluation of a New 18F-Labeled Radiotracer for Studying the GABAB Receptor in the Mouse Brain

Naik, Ravi,Valentine, Heather,Dannals, Robert F.,Wong, Dean F.,Horti, Andrew G.

, p. 1453 - 1461 (2018/06/26)

New GABAB agonists, fluoropyridyl ether analogues of baclofen, have been synthesized as potential PET radiotracers. The compound with highest inhibition binding affinity as well as greatest agonist response, (R)-4-amino-3-(4-chloro-3-((2-fluoro

Discovery of a novel potent GABAB receptor agonist

Xu, Feng,Peng, Ge,Phan, Thu,Dilip, Usha,Chen, Jian Lu,Chernov-Rogan, Tania,Zhang, Xuexiang,Grindstaff, Kent,Annamalai, Thamil,Koller, Kerry,Gallop, Mark A.,Wustrow, David J.

scheme or table, p. 6582 - 6585 (2011/12/04)

Structure-activity studies have led to a discovery of 3-(4-pyridyl)methyl ether derivative 9d that has 25-to 50-fold greater functional potency than R-baclofen at human and rodent GABAB receptors in vitro. Mouse hypothermia studies confirm that this compound crosses the blood-brain barrier and is approximately 50-fold more potent after systemic administration.

GAMMA-AMINO-BUTYRIC ACID DERIVATIVES AS GABAB RECEPTOR LIGANDS

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Page/Page column 52, (2010/11/03)

Gamma-amino-butyric acid derivatives that are GABAB receptor ligands, pharmaceutical compositions comprising such derivatives, and methods of using such derivatives and pharmaceutical compositions thereof for treating diseases are disclosed.

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