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1254730-45-4

C14H18BrNO3 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1254730-45-4 Structure

  • Basic information

    1. Product Name: C14H18BrNO3
    2. Synonyms: C14H18BrNO3
    3. CAS NO:1254730-45-4
    4. Molecular Formula:
    5. Molecular Weight: 328.206
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1254730-45-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C14H18BrNO3(CAS DataBase Reference)
    10. NIST Chemistry Reference: C14H18BrNO3(1254730-45-4)
    11. EPA Substance Registry System: C14H18BrNO3(1254730-45-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1254730-45-4(Hazardous Substances Data)

1254730-45-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1254730-45-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,4,7,3 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1254730-45:
(9*1)+(8*2)+(7*5)+(6*4)+(5*7)+(4*3)+(3*0)+(2*4)+(1*5)=144
144 % 10 = 4
So 1254730-45-4 is a valid CAS Registry Number.

1254730-45-4Downstream Products

1254730-45-4Relevant articles and documents

Intrinsic electrophilicity of the 4-methylsulfonyl-2-pyridone scaffold in glucokinase activators: Role of glutathione-S-transferases and in vivo quantitation of a glutathione conjugate in rats

Litchfield, John,Sharma, Raman,Atkinson, Karen,Filipski, Kevin J.,Wright, Stephen W.,Pfefferkorn, Jeffrey A.,Tan, Beijing,Kosa, Rachel E.,Stevens, Benjamin,Tu, Meihua,Kalgutkar, Amit S.

scheme or table, p. 6262 - 6267 (2010/11/18)

Previous studies on the in vitro metabolism of 4-alkylsulfonyl-2-pyridone- based glucokinase activators revealed a facile, non-enzymatic displacement of the 4-alkylsulfonyl group by glutathione. In the present studies, a role for glutathione-S-transferases (GST) as catalysts in the desulfonylation reaction was demonstrated using a combination of human liver microsomes, human liver cytosol and human GSTs. The identification of a glutathione conjugate in circulation following intravenous administration of a candidate 4-methylsulfonyl-2-pyridone to rats confirmed the relevance of the in vitro findings.

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