1260230-06-5

Basic information

• Product Name: 4-(4-bromophenyl)-1-(1,2,4-triazol-3-yl-carbonyl)-thiosemicarbazide
• Synonyms: 4-(4-bromophenyl)-1-(1,2,4-triazol-3-yl-carbonyl)-thiosemicarbazide
• CAS NO: 1260230-06-5
• Molecular Weight: 341.191
• Mol File: 1260230-06-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-bromophenyl)-1-(1,2,4-triazol-3-yl-carbonyl)-thiosemicarbazide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-bromophenyl)-1-(1,2,4-triazol-3-yl-carbonyl)-thiosemicarbazide(1260230-06-5)
• EPA Substance Registry System: 4-(4-bromophenyl)-1-(1,2,4-triazol-3-yl-carbonyl)-thiosemicarbazide(1260230-06-5)

Safety Data

• Hazardous Substances Data: 1260230-06-5(Hazardous Substances Data)

Upstream product

• 21732-98-9 1H-[1,2,4]triazole-3-carboxylic acid hydrazide 
• 1985-12-2 4-Bromophenyl isothiocyanate 

Downstream Products

• 4928-87-4 1,2,4-triazole-3-carboxylic acid 
• 1260230-13-4 4-(4-bromophenyl)-5-(1,2,4-triazol-3-yl)-s-triazole-3-thione 

Relevant articles and documents

Study of direction of cyclization of 1-azolil-4-aryl/alkyl- thiosemicarbazides

On a four series of 1-azolil-4-aryl/alkyl-thiosemicabazides, a study on the influence of azole moiety on the capability for intramolecular cyclization and its direction was carried out. It was found that for 4-aryl/alkyl- thiosemicabazides with triazole, imidazole, or pyrrole moiety at N-1 nitrogen atom possible products were only s-triazoles, both in alkaline and acidic medium. Successful dehydrocyclization of 1-azolil-4-aryl/alkyl- thiosemicarbazides leading to a thiadiazole has been documented only for a series of 1-(4-methyl-1,2,3-thiadiazol-5-yl-carbonyl)-4-aryl/alkyl- thiosemicarbazides. It can be speculative that the determination of pK a value of oxygen atom of 1-azolil-4-aryl/alkyl-thiosemicarbazide can be a very valuable parameter in the prediction of the possibility of dehydrocyclization to form thiadiazole.