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BOC-L-TYR(ALL)-OH, also known as Boc-Tyr(Allyl)-OH, is a white crystalline powder with unique chemical properties. It is characterized by the presence of a gem-dimethyl substituent, which makes it resistant to Claisen rearrangement in water. BOC-L-TYR(ALL)-OH is a derivative of the amino acid tyrosine, featuring an allyl group attached to the side chain.

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  • 127132-38-1 Structure
  • Basic information

    1. Product Name: BOC-L-TYR(ALL)-OH
    2. Synonyms: N-ALPHA-TERT-BUTYLOXYCARBONYL-O-ALLYL-L-TYROSINE;N-ALPHA-T-BUTYLOXYCARBONYL-O-ALLYL-L-TYROSINE;BOC-TYR(ALL)-OH;BOC-TYR(ALLYL)-OH;BOC-TYR(AL)-OH;BOC-L-TYR(ALL)-OH;BOC-L-TYROSINE ALLYL ESTER;BOC-O-ALLYL-L-TYROSINE
    3. CAS NO:127132-38-1
    4. Molecular Formula: C17H23NO5
    5. Molecular Weight: 321.37
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 127132-38-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 490.39 °C at 760 mmHg
    3. Flash Point: 250.379 °C
    4. Appearance: /
    5. Density: 1.145 g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.526
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. BRN: 3624582
    11. CAS DataBase Reference: BOC-L-TYR(ALL)-OH(CAS DataBase Reference)
    12. NIST Chemistry Reference: BOC-L-TYR(ALL)-OH(127132-38-1)
    13. EPA Substance Registry System: BOC-L-TYR(ALL)-OH(127132-38-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. F: 10-21
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 127132-38-1(Hazardous Substances Data)

127132-38-1 Usage

Uses

Used in Pharmaceutical Industry:
BOC-L-TYR(ALL)-OH is used as an intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its resistance to Claisen rearrangement in water makes it a valuable building block for the development of new drugs with improved stability and efficacy.
Used in Chemical Research:
In the field of chemical research, BOC-L-TYR(ALL)-OH serves as a valuable compound for studying the effects of gem-dimethyl substitution on the reactivity and stability of molecules. This knowledge can be applied to the design of new chemical entities with tailored properties for various applications.
Used in Material Science:
BOC-L-TYR(ALL)-OH can be utilized as a component in the development of novel materials with specific properties, such as enhanced stability or resistance to certain chemical reactions. Its unique chemical characteristics make it a promising candidate for use in the creation of advanced materials for various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 127132-38-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,1,3 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 127132-38:
(8*1)+(7*2)+(6*7)+(5*1)+(4*3)+(3*2)+(2*3)+(1*8)=101
101 % 10 = 1
So 127132-38-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H23NO5/c1-5-10-22-13-8-6-12(7-9-13)11-14(15(19)20)18-16(21)23-17(2,3)4/h5-9,14H,1,10-11H2,2-4H3,(H,18,21)(H,19,20)/t14-/m0/s1

127132-38-1 Well-known Company Product Price

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  • Aldrich

  • (78539)  Boc-Tyr(Allyl)-OH  ≥98.0% (HPLC)

  • 127132-38-1

  • 78539-5G-F

  • 995.67CNY

  • Detail

127132-38-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name BOC-L-TYR(ALL)-OH

1.2 Other means of identification

Product number -
Other names Boc-O-allyl-L-tyrosine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127132-38-1 SDS

127132-38-1Relevant articles and documents

Divergent and site-selective solid-phase synthesis of sulfopeptides

Taleski, Deni,Butler, Stephen J.,Stone, Martin J.,Payne, Richard J.

, p. 1316 - 1320 (2011)

On solid ground: A solid-phase strategy for the efficient synthesis of sulfopeptides is described. Selective deprotection of orthogonally-protected tyrosine residues and solid-phase sulfation provided divergent access to differentially sulfated peptides in high yields. Copyright

Macrocyclic analogues of the diuretic insect neuropeptide helicokinin I show strong receptor-binding

Tran Van, Chien,Nennstiel, Dirk,Scherkenbeck, Jürgen

, p. 3278 - 3286 (2015)

Abstract Helicokinin I, a diuretic neuropeptide of the relevant cotton pest Helicoverpa zea represents a promising target for the design of insect neuropeptide mimetics. Using a ring-closing metathesis reaction, N-terminal bridged macrocyclic helicokinin

Chiral Lewis acids supported on silica gel and alumina, and their use as catalysts in Diels-Alder reactions of methacrolein and bromoacrolein

Fraile, Jose M.,Garcia, Jose I.,Mayoral, Jose A.,Royo, Ana J.

, p. 2263 - 2276 (1996)

Several derivatives of (S)-tyrosine are supported on silica gel through the phenolic oxygen atom. The Lewis acids obtained by treatment of these solids with BH3 are able to promote the reactions of methacrolein and bromoacrolein with cyclopenta

Polymer Attached Cyclic Dipeptides as Catalysts for Enantioselective Cyanohydrin Formation

Kim, Hyun J.,Jackson, W. Roy

, p. 1421 - 1430 (1992)

Derivatives of cyclo-, related to the "Inoue" catalyst, cyclo- have been attached to chloromethylated polystyrene and to polysiloxane polymers via spacer groups coupled to the tyrosine phenolic residue.These polymer-attac

Total Synthesis of the Putative Structure of Asperipin-2a and Stereochemical Reassignment

Hutton, Craig A.,Shabani, Sadegh,White, Jonathan M.

supporting information, p. 7730 - 7734 (2020/10/09)

The total synthesis of the putative structure of asperipin-2a is described. The synthesis features ether cross-links between the phenolic oxygen of Tyr6 and the β position of Tyr3 and the phenolic oxygen of Tyr3 and the β position of Hpp1 in the unique 17- and 14-membered bicyclic structure of asperipin-2a, respectively. The synthesized putative structure does not match the natural product, and a stereochemical reassignment is postulated.

Design and synthesis of β-strand-fixed peptides inhibiting aggregation of amyloid β-protein

Akagi, Ken-ichi,Masuda, Yuichi,Monobe, Yoko,Shibata, Kana,Tanaka, Fumiya

supporting information, (2020/08/07)

Aggregation of 42-residue amyloid β-protein (Aβ42) can be prevented by β-sheet breaker peptides (BSBps) homologous to LVFFA residues, which are included in a β-sheet region of Aβ42 aggregates. To enhance the affinity of BSBps to the Aβ42 aggregates, we de

Novel non-peptide GPIIb/IIIa antagonists: Synthesis and biological activities of 2-[4-[2-(4-amidinobenzoylamino)-2-(substituted)acetyl]-3-(2-methoxy-2- oxoethyl)-2-oxopiperazinyl] acetic acids

Kitamura,Fukushi,Miyawaki,Kawamura,Terashita,Sugihara,Naka

, p. 258 - 267 (2007/10/03)

To improve the in vitro and in vivo potency of our first low molecular weight GPIIb/IIIa antagonist 1 (TAK-029), a series of 2-[4-[2-(4-amidinobenzoylamino)-2-(substituted)acetyl]-3-(2-methoxy-2- oxoethyl)-2-oxopiperazinyl]acetic acids were synthesized th

A4 B6 macrotricyclic enantioselective receptors for amino acid derivatives, and other compounds

-

, (2008/06/13)

The subject invention provides chiral receptor molecules having the structure: STR1 wherein A has the structure: STR2 and R1 and R2 are independently the same or different and are H, F, alkyl, aryl, etc.; X is CH2 or NH; Y is C=O or SO2 ; and n is 0 to about 3; which are useful for the purification of enantiomers of amino acid derivatives and other compounds. The subject invention also provides methods of preparing said receptor molecules.

Enantioselective receptor for amino acid derivatives, and other compounds

-

, (2008/06/13)

The present invention relates to a composition having the general formula: STR1 wherein each of A, B, C, X, Y, and Z is independently O, NH, N(CH2)m CH3 ], N(C=O) (CH2)m CH3 ], CH2, S, or Se; each of R1, R2, and R3 is independently phenyl, 4-hydroxyphenyl, pyridyl, pyrrolyl, indolyl, naphthyl, thiophenyl, (C=O) (CH2)p CH3, NH(C=O) (CH2)p CH3 ], OH, COOH, NH2, or SH; and m, n, and p are integers between 0 and 5. The composition is a chiral receptor molecule useful for the purification of enantiomers of derivatives of amino acids and of compounds able to form hydrogen bonds. The preparation of the composition involves coupling a trifunctional aromatic molecule with three protected chiral molecules at the three aromatic groups, cleaving protecting groups, and joining adjacent chiral groups by multiple lactamizations. The receptor may be used in a form either bound to a solid support or dissolved in an immiscible phase to effect convenient purification of enantiomers or other compounds of interest.

Reductive deprotection of aryl allyl ethers with Pd(Ph3)4/NaBH4

Beugelmans, Rene,Bourdet, Sebastien,Bigot, Antony,Zhu, Jieping

, p. 4349 - 4350 (2007/10/02)

Treatment of aryl allyl ethers with catalytic amounts of Pd(PPh3)4 and NaBH4 at room temperature afforded the parent phenol in high yield under non-hydrolytic conditions.

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