127958-03-6 Usage
General Description
2-Amino-4-isopropylpyrimidine-5-carboxylic acid is a chemical compound with the molecular formula C9H13N3O2. It is an intermediate used in the synthesis of pharmaceuticals and agrochemicals. 2-Amino-4-isopropylpyrimidine-5-carboxylic acid is a pyrimidine derivative that contains an amino group, an isopropyl group, and a carboxylic acid group. It is commonly used as a building block in the production of various drugs and agricultural chemicals due to its ability to serve as a versatile scaffold for creating new compounds with potential biological activity. Additionally, it has been studied for its potential application in the treatment of various diseases and as a precursor for the synthesis of organic materials.
Check Digit Verification of cas no
The CAS Registry Mumber 127958-03-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,9,5 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 127958-03:
(8*1)+(7*2)+(6*7)+(5*9)+(4*5)+(3*8)+(2*0)+(1*3)=156
156 % 10 = 6
So 127958-03-6 is a valid CAS Registry Number.
127958-03-6Relevant articles and documents
Reaction of 2-Dimethylaminomethylene-1,3-diones with Dinucleophiles. VIII. Synthesis of Ethyl and Methyl 2,4-Disubstituted 5-Pyrimidinecarboxylates
Schenone, Pietro,Sansebastiano, Laura,Mosti, Luisa
, p. 295 - 305 (2007/10/02)
Reaction of ethyl or methyl 2-dimethylaminomethylene-3-oxoalkanoates with N-C-N dinucleophiles such as guanidine, acetamidine or benzamidine afforded in high yields the relative esters of 4-substituted 2-amino-, 2-methyl- or 2-phenyl-5-pyrimidinecarboxylic acids, respectively.These esters were hydrolyzed to the corresponding carboxylic acids, which were converted by heating to 4-substituted 2-pyrimidinamines, 2-methyl or 2-phenylpyrimidines, respectively, generally in excellent yields.The 4-unsubstituted ethyl 2-amino-, 2-methyl- and 2-phenyl-5-pyrimidinecarboxylateswere obtained in moderate yields by reaction of the above dinucleophiles with ethyl 2,2-diformylacetate.These esters were hydrolyzed and the corresponding acids (with the exception of the 2-methyl derivative) were decarboxylated to give 2-pyrimidinamine and 2-phenylpyrimidine in satisfactory yields.
