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130309-37-4

FMOC-OIC-OH is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 130309-37-4 Structure

  • Basic information

    1. Product Name: FMOC-OIC-OH
    2. Synonyms: Fmoc-L-octahydroindole-2-carboxylic acid≥ 99% (HPLC);FMOC-OIC-OH;FMOC-L-OIC-OH;FMOC-L-OCTAHYDROINDOLE-2-CARBOXYLIC ACID;(2S,3AS,7AS)-1-FMOC-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID;(2S,3AS,7AS)-FMOC-1-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID;(S)-N-(9-FLUORENYLMETHYLOXYCARBONYL)-OCTAHYDROINDOLECARBOXYLIC ACID;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-OCTAHYDROINDOLE-2-CARBOXYLIC ACID
    3. CAS NO:130309-37-4
    4. Molecular Formula: C24H25NO4
    5. Molecular Weight: 391.46
    6. EINECS: 1312995-182-4
    7. Product Categories: Amino Acids;Unusual Amino Acids
    8. Mol File: 130309-37-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 592.4±33.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: White/Powder
    5. Density: 1.279±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 3.98±0.20(Predicted)
    10. CAS DataBase Reference: FMOC-OIC-OH(CAS DataBase Reference)
    11. NIST Chemistry Reference: FMOC-OIC-OH(130309-37-4)
    12. EPA Substance Registry System: FMOC-OIC-OH(130309-37-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 130309-37-4(Hazardous Substances Data)

130309-37-4 Usage

Chemical Properties

White to off-white powder

Check Digit Verification of cas no

The CAS Registry Mumber 130309-37-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,3,0 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 130309-37:
(8*1)+(7*3)+(6*0)+(5*3)+(4*0)+(3*9)+(2*3)+(1*7)=84
84 % 10 = 4
So 130309-37-4 is a valid CAS Registry Number.

130309-37-4 Well-known Company Product Price

  • Brand
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  • Detail

  • Alfa Aesar

  • (H63491)  (2S,3aS,7aS)-1-Fmoc-octahydroindole-2-carboxylic acid, 98%   

  • 130309-37-4

  • 250mg

  • 796.0CNY

  • Detail

  • Alfa Aesar

  • (H63491)  (2S,3aS,7aS)-1-Fmoc-octahydroindole-2-carboxylic acid, 98%   

  • 130309-37-4

  • 1g

  • 2646.0CNY

  • Detail

130309-37-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name Fmoc-L-Octahydroindole-2-Carboxylic Acid

1.2 Other means of identification

Product number -
Other names (2S,3aS,7aS)-1-(9H-fluoren-9-ylmethoxycarbonyl)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:130309-37-4 SDS

130309-37-4Relevant articles and documents

Exploring hydrophobicity limits of polyproline helix with oligomeric octahydroindole-2-carboxylic acid

Kubyshkin, Vladimir,Budisa, Nediljko

, (2018/03/30)

The polyproline-II helix is the most extended naturally occurring helical structure and is widely present in polar, exposed stretches and “unstructured” denatured regions of polypeptides. Can it be hydrophobic? In this study, we address this question usin

Construction of a polyproline structure with hydrophobic exterior using octahydroindole-2-carboxylic acid

Kubyshkin, Vladimir,Budisa, Nediljko

, p. 619 - 627 (2017/01/25)

The proline analogue (2S,3aS,7aS)-octahydroindole-2-carboxylic acid (Oic) has been previously applied as a proline substitute in pharmocologically active peptides and as a structural component of the antihypertensive drug Perindopril. Herein, we describe the formation of an oligoproline structure by an Oic oligomer. A series of Oic oligomers were investigated to show the structural and energetic contribution of appended residues to the structure. NMR investigation of these oligomers revealed an all-trans amide bond structure, and we provide evidence that a cascade-like mechanism is responsible for the all-trans folding cooperativity. X-ray crystallography of the Oic-hexapeptide clearly demonstrates that the all-trans structure of the Oic oligomer is a polyproline II helix. Thus, as a hydrophobic proline analog with a highly stable trans-amide bond, Oic represents an ideal building block for hydrophobic sites of polyproline II structures in biologically relevant contexts.

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