13101-40-1

Basic information

• Product Name: 1-BROMO-3-CHLORO-5-IODOBENZENE
• Synonyms: 1-BROMO-3-CHLORO-5-IODOBENZENE;3-Bromo-5-chloroiodobenzene
• CAS NO: 13101-40-1
• Molecular Formula: C₆H₃BrClI
• Molecular Weight: 317.35
• Mol File: 13101-40-1.mol

Chemical Properties

• Melting Point: 85.8℃
• Boiling Point: 280.4±25.0℃ (760 Torr)
• Flash Point: 123.4±23.2℃
• Appearance: /
• Density: 2.272±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.00644mmHg at 25°C
• Refractive Index: 1.663
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-BROMO-3-CHLORO-5-IODOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-3-CHLORO-5-IODOBENZENE(13101-40-1)
• EPA Substance Registry System: 1-BROMO-3-CHLORO-5-IODOBENZENE(13101-40-1)

Safety Data

• Hazardous Substances Data: 13101-40-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-Bromo-3-chloro-5-iodobenzene is used as a starting material in the synthesis of various pharmaceuticals. Its presence of multiple halogens on the benzene ring allows for the creation of diverse chemical structures, making it a valuable tool for researchers and chemists in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical industry, 1-Bromo-3-chloro-5-iodobenzene serves as a key intermediate in the production of various agrochemicals. Its unique structure enables the synthesis of compounds with specific properties, such as herbicides, insecticides, and fungicides, contributing to the development of more effective and targeted agricultural solutions.
Used in Material Science:
1-Bromo-3-chloro-5-iodobenzene is utilized in the development of new materials, particularly in the field of organic materials. Its versatile structure allows for the creation of compounds with specific properties, such as conductivity, magnetism, or luminescence, which can be applied in various technological applications.
Used in Organic Synthesis:
As a building block for the synthesis of complex organic molecules, 1-Bromo-3-chloro-5-iodobenzene plays a crucial role in organic synthesis. Its presence of multiple halogens on the benzene ring makes it a valuable precursor for the creation of a wide range of organic compounds, including natural products, pharmaceuticals, and specialty chemicals.

InChI:InChI=1/C6H3BrClI/c7-4-1-5(8)3-6(9)2-4/h1-3H

Upstream product

• 96558-78-0 3-bromo-5-chlorophenylamine 
• 71757-16-9 2-bromo-4-chloro-6-iodoaniline 
• 14862-52-3 1,3-dibromo-5-chlorobenzene 
• 873386-83-5 2-bromo-6-chloro-4-iodoaniline 
• 488850-91-5 2-(3-bromo-5-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 108-37-2 1-bromo-3-chlorobenzene 
• 873-38-1 4-chloro-2-bromoaniline 

Downstream Products

• 1638533-94-4 9-(3-Bromo-5-chlorophenyl)-9H-carbazole 
• 1073062-42-6 2-(3-bromo-5-chlorophenyl )-4,6-diphenyl-1,3,5-triazine 

Relevant articles and documents

COMPOUND, METHOD FOR PREPARING THE SAME, ORGANIC SEMICONDUCTING LAYER, ORGANIC ELECTRONIC DEVICE, DISPLAY DEVICE AND LIGHTING DEVICE COMPRISING THE SAME

The present invention relates to a compound of Formula (I) wherein Ar1 is selected from substituted or unsubstituted C2 to C36heteroaryl and the group Ar1 is bound to the remaining structure represented by Formula (I) via one of its carbon atoms; Ar2 is selected from the group consisting of substituted or unsubstituted C6 to C36aryl and substituted or unsubstituted C4 to C36 heteroaryl comprising at least one heteroatom selected from 0, S and Se, wherein the heteroaryl group comprising at least one heteroatom selected from O, S and Se is bound to the remaining structure represented by Formula (I) via one of its carbon atoms; Ar3 is selected from the group consisting of substituted or unsubstituted C6 to C18 arylene and substituted or unsubstituted C3 to.C18 heteroarylene, wherein it is provided that the group Ar3 comprises not more than three fused rings; wherein, in case that one or more of Ar1, Ar2 and Ar3is substituted, the substituents are each independently selected from the group consisting of D, F, C1 to C20 linear alkyl, C3 to C20branched alkyl, C3 to C20 cyclic alkyl, C1 to C20 linear alkoxy, C3 to C20 branched alkoxy, linear fluorinated C1to C12 allkyl, linear fluorinated C1 to C12 alkoxy, C3 to C12 branched fluorinated cyclic alkyl, C3 to C12 fluorinated cyclic allkyl, C3 to C12 fluorinated cyclic alkoxy, CN, RCN, C6 to C20, aryl, C2 to C20 heteroaryl, OR, SR, (C=0)R, (C=0)NR2, SiR3, (S=0)R, (S=0)2R, (P=0)R2; wherein each R is independently selected from C1to C20 linear alkyl, C1 to C20 alkoxy, C1to C20 thioalkyl, C3to C20 branched alkyl, C3 to C20 cyclic alkyl, C3 to C20 branched alkoxy, C3 to C20 cyclic alkoxy, C3 to C20 branched thioalkyl, C3 to C20 cyclic thioalkyl, C6 to C20 aryl and C2 to C20heteroaryl; and wherein Ar1 and Ar2 are selected differently from each other, a method for preparing the same, an organic semiconducting layer comprising the same, an organic electronic device comprising the same and a display device or a lighting device comprising the organic electronic device.

A 1-chloro-3-bromo-5-iodophenylamino preparation method

This invention relates to a kind of 1-chloro-3-bromo-5-iodophenylamino preparation method, comprising the following steps: step one, in a container into the to iodine aniline and anhydrous ethanol, under normal temperature conditions, batch by adding bromine-chlorine-dimethyl hydantoin; HPLC print detection no raw material product, stopping reaction; can be directly filtered to obtain 2-chloro-4-bromo-6-iodo aniline intermediates; stated, in another container into the 2-chloro-4-bromo-6-iodo aniline intermediate and secondary phosphate, sodium nitrite solution dropwise after cooling, there will be after the end of the dropping solid wash-out, direct filter, recrystallized with absolute ethanol to obtain acicular 1-chloro-3-bromo-5-iodophenylamino. The present invention improves operating environment of production, at the same time adopts a low priced bromine-chlorine-dimethyl hydantoin as the solvent for preparing the product, and is easy to operate and control, and the yield is improved, but also shortens the reaction time, the cost is reduced, which is beneficial for industrial production.

Sterically controlled iodination of arenes via iridium-catalyzed C-H borylation

A mild method to prepare aryl and heteroaryl iodides by sequential C-H borylation and iodination is reported. The regioselectivity of this process is controlled by steric effects on the C-H borylation step and is complementary to existing methods to form aryl iodides. The iodination of boronic esters has potential for the synthesis of radiolabeled aryl iodides, as demonstrated by the concise synthesis of a potential tracer for SPECT imaging.