13170-66-6

Basic information

• Product Name: Cyclohexyl-1,4-dicarboxylchloride
• Synonyms: Cyclohexyl-1,4-dicarboxylchloride;1,4-Cyclohexanedicarbonyl dichloride (9CI);Hexahydroterephthaloyl chloride;CYCLOHEXY 1,4 DICARBOXYLIQUE CHLORIDE;Cyclohexane-1,4-dicarbonyl dichloride;1,4-CYCLOHEXANEDICARBONYL DICHLORIDE
• CAS NO: 13170-66-6
• Molecular Formula: C₈H₁₀Cl₂O₂
• Molecular Weight: 209.071
• Product Categories: ACIDHALIDE
• Mol File: 13170-66-6.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 97-97.5 °C(Press: 0.5 Torr)
• Appearance: /
• Density: 1.2845 g/cm3
• CAS DataBase Reference: Cyclohexyl-1,4-dicarboxylchloride(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexyl-1,4-dicarboxylchloride(13170-66-6)
• EPA Substance Registry System: Cyclohexyl-1,4-dicarboxylchloride(13170-66-6)

Safety Data

• Hazardous Substances Data: 13170-66-6(Hazardous Substances Data)

Usage

Description

Cyclohexyl-1,4-dicarboxylchloride, also known as 1,4-Cyclohexanedicarbonyl chloride, is a widely used chemical compound that is a heavy colorless liquid with a strong, pungent odor. It is produced through several chemical processes involving cyclohexanone and is often used as a precursor to plasticizers and resin intermediates, operating within the larger framework of industrial-grade chemical synthesis.

Uses

Used in Chemical Synthesis Industry:
Cyclohexyl-1,4-dicarboxylchloride is used as a precursor for the production of plasticizers and resin intermediates, contributing to the synthesis of various industrial-grade chemicals.
Used in Plastics Industry:
Cyclohexyl-1,4-dicarboxylchloride is used as a chemical intermediate in the production of plasticizers, which are additives that increase the flexibility and workability of plastics.
Used in Resin Production:
Cyclohexyl-1,4-dicarboxylchloride is used as a chemical intermediate in the synthesis of resins, which are essential components in the manufacturing of various products such as coatings, adhesives, and composite materials.
Safety Precautions:
As with many chemicals of its kind, it is advised to handle Cyclohexyl-1,4-dicarboxylchloride with caution as it can cause skin and eye irritation. Proper safety measures should be taken to minimize the risk of exposure and potential health hazards.

Upstream product

• 14571-47-2 (1s,4s)-cyclohexane-1,4-dicarbonyl dichloride 
• 619-82-9 trans-hexahydroterephthalic acid 
• 94-60-0 dimethyl 1,4-cyclohexane dicarboxylate 
• 619-81-8 cyclohexane-1,4-dicarboxylic acid 

Downstream Products

• 4322-09-2 1,4-dicarbonyl-cyclohexane 
• 1938-00-7 1,4-diphenyl cyclohexane-1,4-dicarboxylate 
• 14818-30-5 trans-1,4-Bis-<1-oxo-3-methyl-4-methoxycarbonyl-buten-(3)-yl>-cyclohexan 
• 57113-55-0 trans-1,4-(4'-n-Butoxyphenyl)cyclohexandicarboxylat 
• 72245-80-8 bis(4-pentyloxyphenyl) trans-1,4-cyclohexanedicarboxylate 
• 72213-12-8 trans-1,4-(4'-n-Hexyloxyphenyl)cyclohexandicarboxylat 
• 26379-55-5 Cyclohexane-1,4-dicarboxylic acid bis-(4-methoxy-phenyl) ester 

Relevant articles and documents

Direction of the Dipole Moment in the Ester Group

The directions of the dipole moments in esters RCOOR' in which R and R' are alkyl or aryl groups have been deduced by analysis of experimental values of dipole moments of six compounds containing two polar groups, one or both of which are esters.New determinations of molecular dipole moments are reported for dimethyl trans-1,4-cyclohexanedicarboxylate and for trans-1,4-cyclohexanediol diacetate.The moment of the ester group is directed (in the positive sense) at an angle τE=123 +/- 3 deg from the R-CO axis in both aromatic and aliphatic esters, formates excepted.

Method for preparing 1, 4-diphenyl cyclohexanedicarboxylate

The invention belongs to the field of chemical synthesis and specifically relates to a method for preparing 1, 4-diphenyl cyclohexanedicarboxylate. The method comprises the following steps: performinga reaction in a solvent under the action of a catalyst

POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY

PROBLEM TO BE SOLVED: To provide a polymerizable compound which has high storage stability and can form a film-like polymer while being difficult to cause alignment defects, where the film-like polymer is less likely to be separated from a substrate even when irradiated with ultraviolet for a long time. SOLUTION: The invention provides a compound represented by general formula (I), and a polymer thereof. A composition comprising the compound is useful as a polymerizable liquid crystal composition. (For example, the compound is bis[4-(acryloyloxyethoxy-ethoxy-ethoxy)phenyl]1,4-cyclohexanedicarboxylate.) SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

Novel bivalent securinine mimetics as topoisomerase I inhibitors

A series of novel bivalent securinine mimetics incorporating different linkers between C-15 and C-15′ were synthesized and their topoisomerase I (Topo I) inhibitory activities evaluated. It was thus revealed that mimetic R2 incorporating a rigid m-substituted benzene linker exhibits Topo I inhibitory activity three times that of parent securinine. Comprehensive structure-activity relationship analyses in combination with docking studies were used to rationalize the potent activity of these bivalent mimetics. Mechanistic studies served to confirm the deductions arising from docking studies that the active bivalent mimetics not only inhibited complexation between Topo I and DNA but also stabilized the Topo I-DNA complex itself.