134603-82-0

Basic information

• Product Name: 1-(2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methanamine
• Synonyms: 1-(2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methanamine
• CAS NO: 134603-82-0
• Molecular Weight: 493.611
• Mol File: 134603-82-0.mol

Chemical Properties

• CAS DataBase Reference: 1-(2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methanamine(134603-82-0)
• EPA Substance Registry System: 1-(2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methanamine(134603-82-0)

Safety Data

• Hazardous Substances Data: 134603-82-0(Hazardous Substances Data)

Upstream product

• 124806-66-2 [2'-(N-Triphenylmethyl-tetrazol-5-yl)-biphenyl-4-yl]methyl azide 
• 905456-93-1 C₄₁H₂₉N₅O₂ 
• 7732-18-5 water 
• 124750-51-2 N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole 

Downstream Products

• 162126-58-1 2-t-Butoxycarbonylamino-N-[[2'-(N-triphenylmethyltetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]acetamide 
• 162126-44-5 (3-phenyl-1-{[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-carbamoyl}-propyl)-carbamic acid tert-butyl ester 
• 162126-49-0 (2-(1-formyl-1H-indol-3-yl)-1-{[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-carbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 745814-08-8 2-(1-TRITYL-1H-TETRAZOL-5-YL)-4'-(1''-ETHOXYPENTANAMINYL)BIPHENYL 
• 22515-76-0 Ammonium methanesulfonate 
• 138402-10-5 trityl irbesartan 
• 905456-94-2 C₃₈H₃₆N₆ 
• 439904-79-7 N-pentanoyl-N-[[2'-[N-(triphenylmethyl)tetrazol-5-yl]-1,1'-biphenyl-4-yl]methyl]amine 
• 905456-95-3 2-butyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carbaldehyde 
• 169598-69-0 5-butyl-2,4-dihydro-4-[[2-(1-triphenylmethyl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4'-yl]methyl]-3H-1,2,4-triazol-3-one 
• 162126-48-9 [1,1-dimethyl-2-(3-phenyl-1-{[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-carbamoyl}-propylcarbamoyl)-ethyl]-carbamic acid benzyl ester 
• 162126-50-3 (2-(1-formyl-1H-indol-3-yl)-1-{[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-carbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 162126-64-9 {1,1-dimethyl-2-[({[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-carbamoyl}-methyl)-carbamoyl]-ethyl}-carbamic acid benzyl ester 

Relevant articles and documents

The discovery and optimization of a series of 2-aminobenzoxazole derivatives as ChemR23 inhibitors

A structural class of 2-aminobenzoxazole derivatives possessing biphenyltetrazole was discovered to be potent human ChemR23 inhibitors. We initially tried to improve the potency of compound 1, which was found through in-house screening using the human pla

METHOD FOR THE PRODUCTION OF LOSARTAN

The invention relates to a novel method for the production of losartan, an imidazol derivative with the chemical name 2-n-butyl-4-chloro-5-hydroxymethyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-]methyl}imidazol and the pharmacologically active salts thereof. The invention also relates to novel intermediate products which are suitable for the production of losartan, and to novel methods for the production of intermediate compounds which are suitable for the production of losartan. One aspect of the invention is a method for the production of a compound of general formula (I), which can arise as an intermediate step in the inventive representation of losartan.

BIPHENYL DERIVATIVES

Biphenyl derivatives represented by the following formula (1): wherein R1 represents a C5-7 alkyl group, R2 represents a substituted or unsubstituted aromatic hydrocarbon, or cycloalkyl group, R3 represents a te