13679-41-9Relevant articles and documents
A New Simple Synthesis of Variously Substituted Furans and Butenolides
Okazaki, Renji,Negishi, Yoshio,Inamoto, Naoki
, p. 1055 - 1056 (1982)
The reaction of 1,2-disubstituted 3,3-bis(methylthio)prop-2-en-1-ones with dimethylsulfonium methylide gave 2,2-bis(methylthio)-2,5-dihydrofurans, useful synthons for a variety of furans and butenolides.
Highly active NHC-Pd(ii) complexes for cross coupling of aryl chlorides and arylboronic acids: An investigation of the effect of remote bulky groups
Han, Fangwai,Xu, Ying,Zhu, Rongjiao,Liu, Guiyan,Chen, Chen,Wang, Jianhui
, p. 7422 - 7427 (2018)
A series of palladium(ii) complexes bearing remote bulky ligands were synthesized and characterized. Their catalytic activity for Suzuki-Miyaura cross-coupling reactions and the effect of remote bulky groups were investigated. These new palladium complexes are highly efficient for the Suzuki-Miyaura cross-coupling reactions of aryl chlorides and arylboronic acids with low catalyst loadings (0.05 mol%) at room temperature in air.
A SIMPLE, EFFICIENT SYNTHESIS OF 3-SUBSTITUTED FURANS
Liotta, Dennis,Saindane, Manohar,Ott, Walter
, p. 2473 - 2476 (1983)
3-Substituted furan can be readily prepared in a single step via a tandem Diels-Alder/retro Diels-Alder reaction between 4-phenyloxazole and simple alkylacetylenes.
An improved synthesis of 3-substituted furans from substituted butene- 1,4-diols
Kraus, George A.,Wang, Xuemei
, p. 1093 - 1096 (1998)
A two-phase mixture of water and hexanes improves the yields of furans produced by the oxidation of butene-1,4-diols.
A Bipyridine-Palladium Derivative as General Pre-Catalyst for Cross-Coupling Reactions in Deep Eutectic Solvents
Saavedra, Beatriz,González-Gallardo, Nerea,Meli, Alessandro,Ramón, Diego J.
supporting information, p. 3868 - 3879 (2019/07/12)
A versatile and DES-compatible bipyridine palladium complex has been developed as a general pre-catalyst for different cross-coupling reactions (Hiyama, Suzuki-Miyaura, Heck-Mizoroki and Sonogashira) in deep eutectic solvents. Hydrogen bond capacity of the ligand allows to keep the excellent level of results previously obtained in classical organic solvents. Palladium pre-catalyst showed a high catalytic activity for many cross-coupling reactions, demonstrating a great versatility and applicability. Also, this methodology employs sustainable solvents as a reaction medium and highlights the potential of DES as alternative solvents in organometallic catalysis. The catalyst and DES were easily and successfully recycled. The formation of PdNPs in DES has been confirmed by TEM and XPS analysis and their role as catalyst by mercury test. The dynamic coordination of bipyridine-type ligand in the palladium complex formation has been studied via UV/Vis. (Figure presented.).
Nickel-Catalyzed Deamidative Step-Down Reduction of Amides to Aromatic Hydrocarbons
Dey, Aniruddha,Sasmal, Sheuli,Seth, Kapileswar,Lahiri, Goutam Kumar,Maiti, Debabrata
, p. 433 - 437 (2017/06/05)
To date, cleavage of the C-N bond in aromatic amides has been achieved in molecules with a distorted constitutional framework around the nitrogen atom. In this report, a nickel-catalyzed reduction of planar amides to the corresponding lower hydrocarbon homologue has been reported. This involves a one-pot reductive cleavage of the C-N bond followed by a tandem C-CO bond break in the presence of a hydride source. Substrate scope circumscribes deamidation examples which proceed via oxidative addition of nickel in the amide bonds of nontwisted amides. Mechanistic studies involving isolation and characterization of involved intermediates via different spectroscopic techniques reveal a deeper introspection into the plausible catalytic cycle for the methodology.
