1575-47-9Relevant articles and documents
Palladium-catalyzed cross-coupling reactions of 4-tosyl-2(5H)-furanone with boronic acids: A facile and efficient route to generate 4-substituted 2(5H)-furanones
Wu, Jie,Zhu, Qiang,Wang, Lisha,Fathi, Reza,Yang, Zhen
, p. 670 - 673 (2003)
An efficient and facile synthesis of 4-substituted 2(5H)-furanones using palladium catalyzed cross-coupling reactions between 4-tosyl-2(5H)-furanone and boronic acids is reported herein.
Palladium-Catalyzed Cross-Coupling of Alkenyl Carboxylates
Becica, Joseph,Heath, Oliver R. J.,Leitch, David C.,Zheng, Cameron H. M.
supporting information, p. 17277 - 17281 (2020/07/31)
Carboxylate esters have many desirable features as electrophiles for catalytic cross-coupling: they are easy to access, robust during multistep synthesis, and mass-efficient in coupling reactions. Alkenyl carboxylates, a class of readily prepared non-aromatic electrophiles, remain difficult to functionalize through cross-coupling. We demonstrate that Pd catalysis is effective for coupling electron-deficient alkenyl carboxylates with arylboronic acids in the absence of base or oxidants. Furthermore, these reactions can proceed by two distinct mechanisms for C?O bond activation. A Pd0/II catalytic cycle is viable when using a Pd0 precatalyst, with turnover-limiting C?O oxidative addition; however, an alternative pathway that involves alkene carbopalladation and β-carboxyl elimination is proposed for PdII precatalysts. This work provides a clear path toward engaging myriad oxygen-based electrophiles in Pd-catalyzed cross-coupling.
Substituted aryl methyl radical Rubrolide compound and its preparation method and application
-
Paragraph 0038; 0050; 0053, (2019/06/12)
The invention discloses a substituted aryl methyl radical Rubrolide compound, its structure is shown as formula I: Wherein R is phenyl, pyridyl, pyrimidinyl, furyl, pyrazolyl, thiazolyl or thienyl, the R is one or more of the substituent of the substituted, the substituted the base is mutual independent, and is selected from one or more saturated or unsaturated alkyl, alkoxy, halogen, fluorine-containing methyl, nitro, cyano, ester or amide. The present invention provides substituted aryl-methyl radical Rubrolide compound of novel structure, which has a broad spectrum of herbicidal activity, can be used for various crops weed control. The invention also provides the preparation method and application.