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Tocopherol, also known as vitamin E, is a fat-soluble antioxidant that plays a crucial role in protecting cells from oxidative damage. It exists in various forms, including α-tocopherol, and is synthesized through methods such as olefin cross-metathesis or condensation reactions using precursors like trimethylhydroquinone and linalool. Its derivatives, like α-tocopherol acetate, are widely used in feed and pharmaceutical industries due to their stability and antioxidant properties. Studies highlight its regeneration mechanisms involving hydroperoxyl radicals and its superior efficacy compared to synthetic antioxidants in inhibiting lipid peroxidation. Efficient synthetic routes, such as those utilizing ruthenium catalysts or cost-effective starting materials, continue to advance its production.

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  • 1406-18-4 Structure
  • Basic information

    1. Product Name: Tocopherol
    2. Synonyms: naturalvitaminee;RAC-ALPHA-TOCOPHEROL;VITAMIN E (DL-FORM);(TOCOPHEROL);TOCOPHEROL, ALPHA-DL-;5,7,8-TRIMETHYLTOCOL;(+/-)-ALPHA-TOCOPHEROL;(+/-)-ALPHA-TOCOFEROL
    3. CAS NO:1406-18-4
    4. Molecular Formula: C29H50O2
    5. Molecular Weight: 430.71
    6. EINECS: 215-798-8
    7. Product Categories: UVCBs-organic
    8. Mol File: 1406-18-4.mol
  • Chemical Properties

    1. Melting Point: 292 °C
    2. Boiling Point: 210ºC at 0.1 mm Hg
    3. Flash Point: 210.2ºC
    4. Appearance: Tan, white granular powder
    5. Density: 0.93 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: 0-6°C
    8. Solubility: N/A
    9. CAS DataBase Reference: Tocopherol(CAS DataBase Reference)
    10. NIST Chemistry Reference: Tocopherol(1406-18-4)
    11. EPA Substance Registry System: Tocopherol(1406-18-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1406-18-4(Hazardous Substances Data)

1406-18-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1406-18-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,0 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1406-18:
(6*1)+(5*4)+(4*0)+(3*6)+(2*1)+(1*8)=54
54 % 10 = 4
So 1406-18-4 is a valid CAS Registry Number.

1406-18-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Tocopherol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1406-18-4 SDS

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1406-18-4Related news

Review ArticleSystematic Review of the Use of Pentoxifylline and Tocopherol (cas 1406-18-4) for the Treatment of Medication Osteonecrosis of the Jaw09/29/2019

ObjectiveMedication-related osteonecrosis of the jaw (MRONJ) is a pathologic process resulting in progressive jawbone destruction. There are no established guidelines for the medical management of MRONJ. Interest in pentoxifylline and tocopherol is growing as they have been shown to be effective...detailed

Identification and expression analysis of alpha Tocopherol (cas 1406-18-4) transfer protein in chickens fed diets containing different concentrations of alpha-Tocopherol (cas 1406-18-4)09/26/2019

Among the eight forms of vitamin E, the liver preferentially releases α-tocopherol into the circulation and it is distributed to the non-liver tissues. In the hepatocytes, alpha tocopherol transfer protein (TTPA) specifically recognizes α-tocopherol with 2R-configuration and facilitates its in...detailed

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