142-48-3

Basic information

• Product Name: STEAROYL SARCOSINE
• Synonyms: STEAROYL SARCOSINE;n-methyl-n-(1-oxooctadecyl)-glycin;N-methyl-N-(1-oxooctadecyl)-Glycine;N-(1-oxooctadecyl)sarcosine;Glycine, N-methyl-N-(1-oxooctadecyl)-;N-STEAROYLSARCOSINE;N-(1-Oxooctadecyl)sarkosin;N-Methyl-N-stearoylglycine
• CAS NO: 142-48-3
• Molecular Formula: C₂₁H₄₁NO₃
• Molecular Weight: 355.56
• EINECS: 205-539-7
• Mol File: 142-48-3.mol

Chemical Properties

• Melting Point: 65-66.5 °C
• Boiling Point: 489.8 °C at 760 mmHg
• Flash Point: 250 °C
• Appearance: /
• Density: 0.95 g/cm³
• Vapor Pressure: 6.19E-11mmHg at 25°C
• Refractive Index: 1.471
• PKA: 3.62±0.10(Predicted)
• CAS DataBase Reference: STEAROYL SARCOSINE(CAS DataBase Reference)
• NIST Chemistry Reference: STEAROYL SARCOSINE(142-48-3)
• EPA Substance Registry System: STEAROYL SARCOSINE(142-48-3)

Safety Data

• Hazardous Substances Data: 142-48-3(Hazardous Substances Data)

Usage

Uses

Used in Cosmetic and Personal Care Industry:
Stearoyl Sarcosine is used as a skin and hair conditioning agent for its ability to improve the texture and appearance of the skin and hair. It provides a smooth and soft feel, making it a popular ingredient in various cosmetic formulations.
Used in Cleansing Products:
Stearoyl Sarcosine is used as a surfactant in cleansing products, such as facial cleansers and body washes, for its ability to effectively remove dirt and oil from the skin. Its surfactant properties help to create a lather that can lift and suspend impurities, making it easier to rinse them away.
Used in Emulsification:
Stearoyl Sarcosine is used as an emulsifying agent in various cosmetic and personal care products to maintain a stable emulsion. It helps to keep the product ingredients from separating, ensuring a uniform mixture and improving the product's performance and shelf life.
It is generally considered safe for use, but like with all chemicals, the concentration is crucial, and it should be used within the recommended amounts to avoid any potential adverse effects.

InChI:InChI=1/C21H41NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20(23)22(2)19-21(24)25/h3-19H2,1-2H3,(H,24,25)

Synthetic route

sarcosine (107-97-1) + Stearoyl chloride (112-76-5) → N-stearoyl sarcosine (142-48-3)

Conditions	Yield
With sodium hydroxide
With water; magnesium oxide

sodium sarcosinate (4316-73-8) + Stearoyl chloride (112-76-5) → N-stearoyl sarcosine (142-48-3)

Conditions	Yield
In water at 40 - 50℃; for 1h; pH 9.5-10.5;

Upstream product

• 4316-73-8 sodium sarcosinate 
• 112-76-5 Stearoyl chloride 
• 107-97-1 sarcosine 

Relevant articles and documents

Synthesis of N-acyl-N-alkylcarboxylates

Chemical synthesis of N-acyl-N-alkylcarboxylates through oxidation of substituted amides formed from carboxylic acid esters and an N-alkyl-N-alkanolamine.

Melting Behaviour of Some Pure N-Acyl Amino Acids and Peptides

Fifty three tlc pure N-acyl amino acids were synthesized by Schotten-Baumann reaction from glc pure odd and even chain fatty acids and chromatographycally homogeneous amino acids and a few N-acyl peptides were prepared through the carboxylic carbonic anhydride intermediates.The melting points are reported and discussed.