1428265-12-6

Basic information

• Product Name: 6-cyclohexyl-2-methylphenanthridine
• Synonyms: 6-cyclohexyl-2-methylphenanthridine
• CAS NO: 1428265-12-6
• Molecular Weight: 275.393
• Mol File: 1428265-12-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 6-cyclohexyl-2-methylphenanthridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-cyclohexyl-2-methylphenanthridine(1428265-12-6)
• EPA Substance Registry System: 6-cyclohexyl-2-methylphenanthridine(1428265-12-6)

Safety Data

• Hazardous Substances Data: 1428265-12-6(Hazardous Substances Data)

Upstream product

• 4441-56-9 cyclohexylboronic acid 
• 1428264-89-4 2-isocyano-5-methyl-1,1'-biphenyl 
• 98-80-6 phenylboronic acid 
• 583-68-6 2-bromo-p-toluidine 
• 42308-28-1 2-amino-5-methylbiphenyl 
• 1428264-96-3 C₁₄H₁₃NO 
• 108-85-0 1-bromocyclohexane 
• 98-89-5 Cyclohexanecarboxylic acid 
• 110-82-7 cyclohexane 
• 42308-22-5 5-methyl-[1,1'-biphenyl]-2-carbonitrile 

Relevant articles and documents

Selective C(sp3)-H activation of simple alkanes: visible light-induced metal-free synthesis of phenanthridines with H2O2as a sustainable oxidant

The visible light-induced metal-free C(sp3)-H phenanthridinylation of simple alkanes with isonitrile is developed with H2O2as a terminal green oxidant. This reaction features good yields and selectivities, mild conditions, and a broad substrate scope with gaseous alkanes involved, allowing practical access to valuable alkyl-substituted phenanthridine derivatives.

Convenient synthesis of 6-alkyl phenanthridines and 1-alkyl isoquinolines via silver-catalyzed oxidative radical decarboxylation

A convenient and efficient protocol for the synthesis of 6-alkyl phenanthridines and 1-alkyl isoquinolines has been developed. The reaction relies on the coupling of 2-isocyanobiphenyls and vinyl isonitriles with alkyl radicals formed by the silver-catalyzed decarboxylation of stoichiometric aliphatic carboxylic acids, and affords diverse phenanthridine and isoquinoline derivatives under mild reaction conditions. The experiment of β-scission of cyclobutylcarbinyl radicals is used to shed light on the reaction mechanism.

A cascade alkylarylation reaction of 2-isocyanobiphenyls with simple alkanes for 6-alkyl phenanthridines via dual C(sp3)-H/C(sp 2)-H functionalizations

A cascade alkylarylation reaction of 2-isocyanobiphenyls with simple alkanes for 6-alkyl phenanthridines has been developed through dual C(sp 3)-H/C(sp2)-H functionalizations. The synthetic method has the advantages of high yields, good compatibility of functional groups and mild reaction conditions, although very unreactive alkanes were involved in the reaction. A plausible mechanism through both copper-catalyzed and DTBP mediated pathways has also been proposed. This journal is the Partner Organisations 2014.