149196-86-1 Usage
Uses
Used in Pharmaceutical Industry:
(R)-3-AMINO-3-(2-PYRIDINYL)PROPIONIC ACID is used as a key intermediate in the synthesis of drugs for the treatment of neurological disorders and central nervous system conditions. Its unique structure allows for the development of novel therapeutic agents with improved efficacy and selectivity.
Used in Drug Discovery and Development:
(R)-3-AMINO-3-(2-PYRIDINYL)PROPIONIC ACID serves as a building block for the synthesis of other bioactive molecules, contributing to the discovery and development of new drugs with potential applications in various therapeutic areas. Its versatile chemical properties enable the design and synthesis of innovative drug candidates with improved pharmacological profiles.
Used in Medicinal Chemistry Research:
(R)-3-AMINO-3-(2-PYRIDINYL)PROPIONIC ACID is utilized in medicinal chemistry research to explore its potential as a therapeutic agent and to understand its interactions with biological targets. This knowledge aids in the optimization of drug candidates and the development of more effective treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 149196-86-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,1,9 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 149196-86:
(8*1)+(7*4)+(6*9)+(5*1)+(4*9)+(3*6)+(2*8)+(1*6)=171
171 % 10 = 1
So 149196-86-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O2/c9-6(5-8(11)12)7-3-1-2-4-10-7/h1-4,6H,5,9H2,(H,11,12)/t6-/m1/s1
149196-86-1Relevant articles and documents
Burkholderia cepacia lipase is an excellent enzyme for the enantioselective hydrolysis of β-heteroaryl-β-amino esters
Tasnadi, Gabor,Forro, Eniko,Fueloep, Ferenc
experimental part, p. 1771 - 1777 (2009/12/28)
The enantioselective (E >200) lipase PS-catalysed hydrolysis of β-heteroaryl-β-amino esters is described. The reactions were performed with H2O (0.5 equiv) in either diisopropyl ether or tert-butyl methyl ether at 25 °C. The resulting β-heteroaryl-substituted β-amino acid enantiomers were formed in high enantiomeric excess (ee ≥ 97%) and in good yield (≥40%).