149455-36-7

Basic information

• Product Name: 6,6-dimethyl-5-oxo-8-(2-oxopyridin-1(2H)-yl)-5,6-dihydronaphthalene-2-carbonitrile
• Synonyms: 2-naphthalenecarbonitrile, 5,6-dihydro-6,6-dimethyl-5-oxo-8-(2-oxo-1(2H)-pyridinyl)-
• CAS NO: 149455-36-7
• Molecular Formula: C₁₈H₁₄N₂O₂
• Molecular Weight: 290.316
• Mol File: 149455-36-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 543.3°C at 760 mmHg
• Flash Point: 282.4°C
• Density: 1.3g/cm³
• Vapor Pressure: 7.26E-12mmHg at 25°C
• Refractive Index: 1.655
• CAS DataBase Reference: 6,6-dimethyl-5-oxo-8-(2-oxopyridin-1(2H)-yl)-5,6-dihydronaphthalene-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6,6-dimethyl-5-oxo-8-(2-oxopyridin-1(2H)-yl)-5,6-dihydronaphthalene-2-carbonitrile(149455-36-7)
• EPA Substance Registry System: 6,6-dimethyl-5-oxo-8-(2-oxopyridin-1(2H)-yl)-5,6-dihydronaphthalene-2-carbonitrile(149455-36-7)

Safety Data

• Hazardous Substances Data: 149455-36-7(Hazardous Substances Data)

Upstream product

• 18292-04-1 2-(trimethylsilyloxy)pyridine 
• 142-08-5 2-hydroxypyridin 
• 544-92-3 copper(I) cyanide 

Relevant articles and documents

2,2-Dialkylnaphthalen-1-ones as new potassium channel activators

A new series of 2,2-dialkylnaphthalen-1-one potassium channel activators has been prepared, and their in vitro relaxant activities in isolated rat portal vein and guinea pig tracheal spirals as well as their oral antihypertensive effect in spontaneously hypertensive rats have been evaluated. The group of 1,2-dihydro-4-(1,2-dihydro-2-oxo-1-pyridyl)-2,2- dimethylnaphthalen-1-ones with an electron-withdrawing substituent at the 6- position contain the most active compounds and 1,2-dihydro-4-(1,2-dihydro-2- oxo-1-pyridyl)-2,2-dimethyl-1-oxonaphthalene-6-carbonitrile, 17f (UR-8225), has been selected for further pharmacological development.