153435-63-3

Basic information

• Product Name: 2-(Tributylstannyl)pyrimidine
• Synonyms: 2-(tri-n-butylstannyl)pyrimidine;2-(Tributylstannyl)pyrimidine ,97%;(Pyrimidin-2-yl)tributylstannane;2-(Tributylstannanyl)pyrimidine;Tributyl(2-pyrimidyl)stannane;PyriMidine,2-(tributylstannyl)-;(Pyrimidin-2-yl)tributylstannane, 2-(Tributylstannyl)-1,3-diazine;2-tributyltinpyrMidine
• CAS NO: 153435-63-3
• Molecular Formula: C₁₆H₃₀N₂Sn
• Molecular Weight: 369.12
• Product Categories: Organostannes;Pyrimidine;Tributylstanny;organic tin
• Mol File: 153435-63-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 381.167 °C at 760 mmHg
• Flash Point: >110℃
• Appearance: /
• Density: 1.164 g/mL at 25 °C
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: n20/D1.512
• Storage Temp.: Keep Cold
• PKA: 1.42±0.33(Predicted)
• CAS DataBase Reference: 2-(Tributylstannyl)pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Tributylstannyl)pyrimidine(153435-63-3)
• EPA Substance Registry System: 2-(Tributylstannyl)pyrimidine(153435-63-3)

Safety Data

• Hazard Codes: Xi,T,N
• Statements: 21-25-36/38-48/23/25-50/53
• Safety Statements: 36/37/39-45-60-61-35
• RIDADR: UN 2788 6.1 / PGIII
• WGK Germany: 3
• HazardClass: IRRITANT, TOXIC, KEEP COLD
• Hazardous Substances Data: 153435-63-3(Hazardous Substances Data)

Usage

Chemical Properties

Clear colorless liquid

Uses

2-(Tributylstannyl)pyrimidine is an organotin compound used in Stille coupling reaction. This can be used as one of the precursors in the synthesis of 2-aminopyridine oxazolidinones as potent and selective tankyrase (TNKS) inhibitors and the synthesis of canagliflozin, a novel inhibitor for sodium-dependent glucose cotransporter.It can also be used in the preparation of various (2-pyrimidyl)silanes.

InChI:InChI=1/C4H3N2.3C4H9.Sn/c1-2-5-4-6-3-1;3*1-3-4-2;/h1-3H;3*1,3-4H2,2H3;/rC16H30N2Sn/c1-4-7-13-19(14-8-5-2,15-9-6-3)16-17-11-10-12-18-16/h10-12H,4-9,13-15H2,1-3H3

Upstream product

• 1722-12-9 2-chloropyrimidine 
• 688-73-3 tri-n-butyl-tin hydride 
• 4226-01-1 tributylstannyllithium 
• 4595-60-2 2-bromopyrimidine 

Downstream Products

• 7431-45-0 2-phenylpyrimidine 
• 872853-40-2 3-(2-chloro-6-fluorophenyl)-2,4-dichloro-6-(pyrimidin-2-yl)-pyridine 
• 1309475-64-6 3-fluoro-4-((5R,7S)-7-hydroxy-7-(3-(pyrimidin-2-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)benzonitrile 
• 1407830-10-7 6-(4-chlorophenyl)-1-methyl-8-(pyrimidin-2-yl)-5,6-dihydro-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepine 
• 1608482-79-6 2-(4-chloro-6-(4-isopropoxyphenyl)pyridin-2-yl)pyrimidine 
• 1456892-20-8 (5-chloro-2-(pyrimidin-2-yl)phenyl)((1S,3S,6R)-3-(((5-chloropyridin-2-yl)amino)methyl)-2-azabicyclo[4.1.0]heptan-2-yl)methanone 
• 1597527-79-1 methyl 5-methoxy-4-methyl-2-(pyrimidin-2-yl)benzoate 

Relevant articles and documents

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