158393-05-6Relevant articles and documents
Synthesis of bicyclic proline derivatives by the aza-Cope-Mannich reaction: Formal synthesis of (±)-acetylaranotin
Belov, Dmitry S.,Ratmanova, Nina K.,Andreev, Ivan A.,Kurkin, Alexander V.
, p. 4141 - 4147 (2015)
Herein we suggest an approach to oxygenated bicyclic amino acids based on an aza-Cope-Mannich rearrangement. Seven distinct amino acid scaffolds analogous to the natural products were prepared on a gram scale with precise control of stereochemistry. Successful implementation of our strategy resulted in the formal synthesis of acetylaranotin.
Syntheses and X-Ray Crystal Structures of Tricyclic Ketones Containing Trans-Fused Azabicyclooctane Units
Mori, Miwako,Saitoh, Fumihiko,Uesaka, Noriaki,Okamura, Kimio,Date, Tadamasa
, p. 4993 - 4998 (2007/10/02)
Tricyclic ketones containing the trans-fused 3-azabicyclooctane framework were prepared from the reactions of dienes and Cp2ZrBu2, followed by treatment with carbon monoxide.The structures were confirmed by X-ray analysis.
