1592-59-2

Basic information

• Product Name: (1RS,2SR)-2-chloro-1-methyl-2-phenyl-ethylamine; hydrochloride
• CAS NO: 1592-59-2
• Molecular Weight: 206.115
• Mol File: 1592-59-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1RS,2SR)-2-chloro-1-methyl-2-phenyl-ethylamine; hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (1RS,2SR)-2-chloro-1-methyl-2-phenyl-ethylamine; hydrochloride(1592-59-2)
• EPA Substance Registry System: (1RS,2SR)-2-chloro-1-methyl-2-phenyl-ethylamine; hydrochloride(1592-59-2)

Safety Data

• Hazardous Substances Data: 1592-59-2(Hazardous Substances Data)

Upstream product

• 38222-77-4 trans-2,5-diphenyl-4-methyl-1,3-oxazoline 
• 38222-78-5 threo-1-benzoyloxy-1-phenyl-2-propylammonium chloride 
• 154-41-6 threo-1-phenyl-1-hydroxy-2-propylammonium chloride 
• 154-41-6 erythro-1-phenyl-1-hydroxy-2-propylammonium chloride 
• 4380-71-6 erythro-2-benzoylamino-1-phenylpropan-1-ol 

Downstream Products

• 78373-96-3 cis-5-phenyl-2-methoxy-4-methyl-1,3-thiazoline 
• 78374-02-4 cis-2-diethylamino-5-phenyl-4-methyl-1,3-thiazoline 
• 78374-00-2 cis-5-phenyl-2-phenylamino-4-methyl-1,3-thiazoline 
• 1630-31-5 cis-5-phenyl-4-methyl-1,3-thiazolidine-2-thione 
• 78393-88-1 threo-1-chloro-1-phenyl-2-isothiocyanatopropane 
• 16251-45-9 4,5-trans-4-Methyl-5-phenyl-1,3-oxazolidin-2-one 

Relevant articles and documents

STEREOCHEMICAL COURSE OF THE REACTION OF 2-HALOETHYL ISOTHIOCYANATES WITH NUCLEOPHILES. sTEREOSPECIFIC ROUTE TO 4,5-DISUBSTITUTED Δ2-THIAZOLINES AND THIAZOLIDINE-2-THIONES

Diastereoisomeric 1-chloro-1-phenyl-2-isothiocyanatopropanes have been prepared.They reacted stereospecifically with CH3ONa, diethylamine, aniline and NaSH to give pure cis or trans-4,5-disubstituted Δ2-thiazolines and thiazolidine-2-thiones whose configuration was determined using the nuclear Overhauser effect.The preponderant conformation of diastereoisomeric 1-chloro-1-phenyl-2-isothiocyanatopropanes was estimated on the basis of coupling constants of vicinal protons.