15953-73-8

Basic information

• Product Name: 4-CHLORO-3,5-DIMETHYL-1H-PYRAZOLE
• Synonyms: AKOS B001465;4-CHLORO-3,5-DIMETHYL-1H-PYRAZOLE;ART-CHEM-BB B001465;4-chloro-3,5-dimethyl-1H-pyrazole(SALTDATA: FREE);1H-Pyrazole,4-chloro-3,5-dimethyl-
• CAS NO: 15953-73-8
• Molecular Formula: C₅H₇ClN₂
• Molecular Weight: 130.58
• Mol File: 15953-73-8.mol

Chemical Properties

• Melting Point: 117.5°C
• Boiling Point: 209.41°C (rough estimate)
• Flash Point: 115.9°C
• Appearance: /
• Density: 1.1900 (rough estimate)
• Vapor Pressure: 0.163mmHg at 25°C
• Refractive Index: 1.4877 (estimate)
• CAS DataBase Reference: 4-CHLORO-3,5-DIMETHYL-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-3,5-DIMETHYL-1H-PYRAZOLE(15953-73-8)
• EPA Substance Registry System: 4-CHLORO-3,5-DIMETHYL-1H-PYRAZOLE(15953-73-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 15953-73-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-CHLORO-3,5-DIMETHYL-1H-PYRAZOLE is used as an intermediate in the synthesis of various drugs. Its unique structure and reactivity contribute to the development of new pharmaceutical compounds, enhancing the range of available treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 4-CHLORO-3,5-DIMETHYL-1H-PYRAZOLE is employed as an intermediate for the production of pesticides. Its chemical properties allow for the creation of effective pest control agents, supporting agricultural productivity.
Used in Research and Development:
4-CHLORO-3,5-DIMETHYL-1H-PYRAZOLE is utilized as a research chemical, aiding in the exploration and development of new molecules and materials. Its presence in the laboratory setting is crucial for advancing scientific understanding and innovation across various industries.

InChI:InChI=1/C5H7ClN2/c1-3-5(6)4(2)8-7-3/h1-2H3,(H,7,8)

Upstream product

• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 7791-25-5 sulfuryl dichloride 
• 60-29-7 diethyl ether 
• 7732-18-5 water 
• 7782-50-5 chlorine 
• 110-91-8 morpholine 
• 270588-84-6 3,6-bis(4-chloro-3,5-dimethylpyrazol-1-yl)-1,2,4,5-tetrazine 
• 106-49-0 p-toluidine 
• 1694-29-7 3-chloropentane-2,4-dione 
• 30169-25-6 3,6-bis-(3,5-dimethyl-pyrazol-1-yl)-1,2,4,5-tetrazine 
• 67940-38-9 boron 2,2-difluoro-5-bromo-4,6-dimethyl-1,3,2-dioxaborin 
• 1186339-57-0 F₂BCH₃COCOCCH₃OSO₂C₆H₅ 
• 123-54-6 acetylacetone 

Downstream Products

• 56079-15-3 4-chloro-1,3,5-trimethyl-1H-pyrazole 
• 113387-69-2 3-(4-Chloro-3,5-dimethyl-pyrazol-1-yl)-thieno[2,3-d]isothiazole 1,1-dioxide 
• 113387-63-6 3-(4-Chloro-3,5-dimethyl-pyrazol-1-yl)-thieno[3,4-d]isothiazole 1,1-dioxide 
• 113387-74-9 3-(4-Chloro-3,5-dimethyl-pyrazol-1-yl)-5-phenyl-thieno[2,3-d]isothiazole 1,1-dioxide 
• 133047-68-4 2-(4-chloro-3,5-dimethylpyrazol-1-yl)-1,4-dihydroxybenzene 
• 133047-74-2 2,3-bis(4-chloro-3,5-dimethylpyrazol-1-yl)-1,4-dihydroxybenzene 
• 1403765-27-4 C₅H₇ClN₂*C₇H₄N₂O₆ 
• 1403765-26-3 C₅H₇ClN₂*C₈H₈O₄ 
• 29400-84-8 4-chloro-5-methyl-1H-pyrazole-3-carboxylic acid 
• 312310-61-5 5-((4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl)furan-2-carboxylic acid 
• 374913-86-7 2-(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)acetic acid 
• 1385804-03-4 C₁₂H₁₂ClN₃O₂ 
• 1385804-05-6 C₁₂H₁₄ClN₃ 

Relevant articles and documents

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Site-Selective C–H Functionalization of (Hetero)Arenes via Transient, Non-symmetric Iodanes

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Cu1.5PMo12O40-catalyzed condensation cyclization for the synthesis of substituted pyrazoles

A convenient and direct approach has been developed for the preparation of pyrazole derivatives by the condensation cyclization of hydrazines/hydrazide and 1,3-diketones in the presence of Cu1.5PMo12O40 (0.33?mol%) under mild conditions (r.t.-60?°C, 10–30?min). Notably, the reaction was found to be scalable as 99% yield was obtained when the reaction was performed at a 5-mmol scale. This solvent-free and halogen-free catalytic system represents an effective economic and environmentally friendly method for the construction of pyrazoles.

A mild halogenation of pyrazoles using sodium halide salts and Oxone

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