16108-03-5

Basic information

• Product Name: N-FORMYL-DL-TRYPTOPHAN
• Synonyms: 2-ForMaMido-3-(1H-indol-3-yl)propanoic acid;Tryptophan, N-formyl-;FOR-DL-TRP-OH;N-FORMYL-DL-TRYPTOPHAN;NALPHA-FORMYL-DL-TRYPTOPHAN;Formyl-DL-Trp-OH;Formyltryptophan;N-FORMYL-DL-TRYPTOPHAN 99+%
• CAS NO: 16108-03-5
• Molecular Formula: C₁₂H₁₂N₂O₃
• Molecular Weight: 232.24
• Product Categories: Amino Acids and Derivatives;Indoles;Tryptophans;Amino Acid Derivatives
• Mol File: 16108-03-5.mol

Chemical Properties

• Melting Point: 167°C
• Boiling Point: 590.378 °C at 760 mmHg
• Flash Point: 310.85 °C
• Appearance: /
• Density: 1.376 g/cm³
• Vapor Pressure: 8.77E-15mmHg at 25°C
• Refractive Index: 1.664
• Storage Temp.: -20°C
• Solubility: almost transparency in hot Methanol
• PKA: 3.49±0.10(Predicted)
• CAS DataBase Reference: N-FORMYL-DL-TRYPTOPHAN(CAS DataBase Reference)
• NIST Chemistry Reference: N-FORMYL-DL-TRYPTOPHAN(16108-03-5)
• EPA Substance Registry System: N-FORMYL-DL-TRYPTOPHAN(16108-03-5)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 16108-03-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
N-Formyl-DL-Tryptophan is used as a potential active ingredient for the development of antidepressant and sleep aid medications, given its association with serotonin production, which is a key neurotransmitter in mood regulation and sleep patterns.
Used in Research and Development:
N-Formyl-DL-Tryptophan is utilized in scientific research to explore its medicinal properties, mode of action, and potential applications in the treatment of various conditions related to mood and sleep disorders. This research is crucial for understanding its pharmacokinetics and identifying any possible side effects before it can be widely adopted in pharmaceutical formulations.

InChI:InChI=1/C12H12N2O3/c15-7-14-11(12(16)17)5-8-6-13-10-4-2-1-3-9(8)10/h1-4,6-7,11,13H,5H2,(H,14,15)(H,16,17)

Upstream product

• 54132-15-9 formylamino-indol-3-ylmethyl-malonic acid dimethyl ester 
• 64-18-6 formic acid 
• 54-12-6 Trp 
• 93033-03-5 N-[2-Benzoimidazol-1-yl-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-formamide 
• 46397-90-4 N-[(1H-indol-3-yl)methyl]-N-ethylethanamine 

Downstream Products

• 73-22-3 L-Tryptophan 
• 38854-43-2 N^α-Formyl-D-tryptophan 
• 27520-72-5 N-formyl-L-tryptophan 
• 134558-09-1 (+/-)-benzyl-N-formyltryptophan 
• 134558-11-5 Methyl-(+/-)-β-amino-β[(phenylmethoxy)carbonyl]-1H-indole-3-butanoate 
• 134558-10-4 1-<(1,1-dimethylethoxy)carbonyl>-N-formyl-DL-tryptophan benzyl ester 
• 136019-52-8 benzyl-(+/-)-α-cyano-1-<(1,1-dimethylethoxy)carbonyl>-1H-indole-3-propanoate 
• 135998-70-8 methyl-(+/-)-β-cyano-1-<(1,1-dimethylethoxy)carbonyl>-β-<(phenylmethoxy)carbonyl>-1H-indole 3-butanoate 
• 134558-12-6 methyl-(+/-)-β-<(phenylmethoxy)carbonyl>-β-<<(tricycl<3.3.1.1>dec-2-yloxy)carbonyl>amino>-1H-indole-3-butanoate 
• 136019-53-9 tricyclo<3.3.1.1>dec-2-yl-(+/-)-<3-(1H-indol-3-ylmethyl)-2,5-dioxo-1-(2-phenylethyl)-3-pyrrolidinyl>carbamate 
• 136019-51-7 (+/-)-β-<<(2-phenylethyl)amino>carbonyl>-β-<<(tricyclo<3.3.1.1>dec-2-yloxy)carbonyl>amino>-1H-indole-3-butanoic acid 
• 135998-76-4 benzyl-(+/-)-β-carboxyl-β-<<(tricyclo<3.3.1.1>dec-2-yloxy)carbonyl>amino>-1H-indole-3-butanoate 
• 134557-58-7 methyl-(+/-)-β-<<(2-phenylethyl)amino>carbonyl>-β-<<(tricyclo<3.3.1.1>dec-2-yloxy)carbonyl>amino>-1H-indole-3-butanoate 
• 135998-74-2 phenylmethyl-(+/-)-β-cyano-1-<(1,1-dimethylethoxy)carbonyl>-β-<β-2-(trimethylsilyl)ethoxycarbonyl>-1H-indole-3-butanoate 

Relevant articles and documents

SYNTHESIS AND REACTIVITY OF THE BENZIMIDAZOLIDES OF N-FORMYLATED AND N-PROTONATED AMINO ACIDS

The reactivity of the benzimidazolides of N-formylated and N-protonated amino acids was studied, and it was shown that they can be used in the synthesis of O-aminoacyl derivatives of nucleotides.