16118-36-8

Basic information

• Product Name: H-DL-MET-OME HCL
• Synonyms: METHYL 2-AMINO-4-(METHYLTHIO)BUTANOATE HYDROCHLORIDE;DL-METHIONINE-OME HCL;DL-METHIONINE METHYL ESTER HCL;DL-METHIONINE METHYL ESTER HYDROCHLORIDE;H-DL-MET-OME HCL;TIMTEC-BB SBB003548;methyl DL-methionate hydrochloride;DL-methioninemethylesterHCl95+%
• CAS NO: 16118-36-8
• Molecular Formula: C₆H₁₄NO₂S*Cl
• Molecular Weight: 199.7
• EINECS: 240-285-0
• Mol File: 16118-36-8.mol

Chemical Properties

• Boiling Point: 277.6 °C at 760 mmHg
• Flash Point: 121.7 °C
• Appearance: /
• Vapor Pressure: 0.0388mmHg at 25°C
• Storage Temp.: −20°C
• Stability: Hygroscopic
• CAS DataBase Reference: H-DL-MET-OME HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-DL-MET-OME HCL(16118-36-8)
• EPA Substance Registry System: H-DL-MET-OME HCL(16118-36-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 16118-36-8(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white powder

InChI:InChI=1/C6H13NO2S.ClH/c1-9-6(8)5(7)3-4-10-2;/h5H,3-4,7H2,1-2H3;1H/t5-;/m0./s1

Upstream product

• 67-56-1 methanol 
• 59-51-8 DL-methionine 
• 10332-17-9 DL-methionine methyl ester 

Downstream Products

• 62605-38-3 N-[N-(4-methoxy-benzyloxycarbonyl)-methionyl]-glycine 
• 145401-87-2 (R)-α-methylbenzylcarbamoyl-DL-methionine methyl ester 
• 26061-07-4 Boc-Phe-Met-OMe 
• 121142-91-4 N-<1-carbomethoxy-3-(methylthio)propyl>-N'-carbobenzyloxysulfamide 
• 6810-12-4 s-methionine hydrochloride 
• 871332-24-0 methyl {4-[{[2-amino-4-(4-phenylpiperazin-1-yl)-1,3,5-triazin-6-yl]methyl}amino]benzoyl}methioninate 
• 2791-03-9 2-{2-[2-(2-tert-Butoxycarbonylamino-3-hydroxy-propionylamino)-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-4-methylsulfanyl-butyric acid methyl ester 
• 69872-63-5 Boc-Gly-Phe-Met-OMe 
• 40290-65-1 H-Phe-Met-OMe*HCl 

Relevant articles and documents

Adducts of rhodium(II) tetraacylates with methionine and its derivatives: 1H and 13C nuclear magnetic resonance spectroscopy and chiral recognition

Complexation of rhodium(II) dimeric tetraacylates: tetraacetate Rh 2AcO4, tetratrifluoroacetate Rh2TFA4 , and (S)-Mosher's acid salt Rh2MTPA4 with both enantiomerically pure and racemic met

Methionine derivate corrosion inhibitor for steel pickling and compounding method thereof

The invention relates to a methionine derivate corrosion inhibitor for steel pickling and a compounding method thereof. The name of the methionine derivate corrosion inhibitor is 2-amino-3-methylmercapto-N-octyl-butyrylamide. The derivate is capable of spontaneously and effectively absorbing the steel surface, is principal in chemical absorption and is higher in adsorption capacity. The introduced carbon chain contains 8 carbon atoms, so that the derivate is higher in water solubility in the use concentration scope and the inhibition efficiency is above 98%.

Regiodivergent Enantioselective γ-Additions of Oxazolones to 2,3-Butadienoates Catalyzed by Phosphines: Synthesis of α,α-Disubstituted α-Amino Acids and N,O-Acetal Derivatives

Phosphine-catalyzed regiodivergent enantioselective C-2- and C-4-selective γ-additions of oxazolones to 2,3-butadienoates have been developed. The C-4-selective γ-addition of oxazolones occurred in a highly enantioselective manner when 2-aryl-4-alkyloxazol-5-(4H)-ones were employed as pronucleophiles. With the employment of 2-alkyl-4-aryloxazol-5-(4H)-ones as the donor, C-2-selective γ-addition of oxazolones took place in a highly enantioselective manner. The C-4-selective adducts provided rapid access to optically enriched α,α-disubstituted α-amino acid derivatives, and the C-2-selective products led to facile synthesis of chiral N,O-acetals and γ-lactols. Theoretical studies via DFT calculations suggested that the origin of the observed regioselectivity was due to the distortion energy that resulted from the interaction between the nucleophilic oxazolide and the electrophilic phosphonium intermediate.

Highly tunable arylated cinchona alkaloids as bifunctional catalysts

We report the design and evaluation of a library of chiral bifunctional organocatalysts in which the distance between the catalytically active units can be systematically varied.

Structural diversity-guided convenient construction of functionalized polysubstituted butenolides and lactam derivatives

A molecular diversity-oriented convenient access to multi-substituted butenolides and lactam scaffolds via four different methods from various phenylacetic acid derivatives is described. The target molecules have been identified on the basis of analytical spectra data, and are useful synthons in the fields of medicine and agrochemicals.

Probing the efficiency of N-heterocyclic carbene promoted O- to C-carboxyl transfer of oxazolyl carbonates

(Chemical Equation Presented) Screening of a range of azolium salts, bases and solvents for reactivity indicates that triazolinylidenes, generated in situ with KHMDS in THF, promote the Steglich rearrangement of oxazolyl carbonates with high catalytic efficiency (typical reaction time 5 min at 1.5 mol % NHC). This protocol shows wide substrate applicability, even allowing the efficient generation of vicinal quaternary centers. An improved experimental procedure is also described that allows a simplified one-pot reaction protocol to be employed with similarly high catalytic efficiency.

New 2-(2'-phenyl-9'-benzyl-8'-azapurin-6'-ylamino)-carboxylic acid methylesters as ligands for A1 adenosine receptors.

Synthesis of a series of new 2-phenyl-9-benzyl-8-azaadenines bearing on N6 an alkyl or aralkyl chain having a carbonyloxymethyl group on the carbon bound to N6 were reported. The ester group could assure to the molecule a better water-solubility than the 8-azaadenines 2, 6 and 9 substituted with lipophilic groups synthesised in the past. Compounds synthesised demonstrated only little capability of binding A1 adenosine receptors.