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S-Cbz-L-cysteine, with the molecular formula C11H13NO4S and a molecular weight of 259.29 g/mol, is a derivative of the amino acid cysteine. The amine group in this compound is protected by a carbobenzyloxy (Cbz) group, which enables selective orthogonal deprotection of other functional groups in a molecule. This feature makes S-Cbz-L-cysteine a valuable building block in organic synthesis and peptide chemistry for constructing complex molecules and peptides. It is a white to off-white solid that is soluble in organic solvents and is typically used in chemical reactions under mild conditions.

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  • 1625-72-5 Structure
  • Basic information

    1. Product Name: S-Cbz-L-cysteine
    2. Synonyms: S-CBZ-L-CYSTEINE;S-Z-L-CYSTEINE;H-CYS(Z)-OH;N-BENZYLOXYCARBONYL-L-CYSTEINE;S-CBZ-L-CYSTEINE CRYSTALLINE;l-cysteine(z)-oh;H-Cys(Cbz)-OH;Nε-Carbobenzyloxy-L-cysteine
    3. CAS NO:1625-72-5
    4. Molecular Formula: C11H13NO4S
    5. Molecular Weight: 255.29
    6. EINECS: N/A
    7. Product Categories: Amino Acids Derivatives;Cysteine [Cys, C];A - H;Amino Acids;Modified Amino Acids
    8. Mol File: 1625-72-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 435.6°Cat760mmHg
    3. Flash Point: 217.2°C
    4. Appearance: /
    5. Density: 1.358g/cm3
    6. Vapor Pressure: 2.33E-08mmHg at 25°C
    7. Refractive Index: 1.602
    8. Storage Temp.: −20°C
    9. Solubility: N/A
    10. PKA: 1.93±0.10(Predicted)
    11. CAS DataBase Reference: S-Cbz-L-cysteine(CAS DataBase Reference)
    12. NIST Chemistry Reference: S-Cbz-L-cysteine(1625-72-5)
    13. EPA Substance Registry System: S-Cbz-L-cysteine(1625-72-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1625-72-5(Hazardous Substances Data)

1625-72-5 Usage

Uses

Used in Organic Synthesis:
S-Cbz-L-cysteine is used as a building block for the synthesis of complex organic molecules. Its protected amine group allows for selective reactions and deprotection, facilitating the creation of a wide range of compounds.
Used in Peptide Chemistry:
In peptide chemistry, S-Cbz-L-cysteine serves as a crucial component for the assembly of peptides. The carbobenzyloxy protection ensures that the amine group can be selectively deprotected, enabling the formation of peptide bonds without unwanted side reactions.
Used in Pharmaceutical Industry:
S-Cbz-L-cysteine is used as an intermediate in the synthesis of pharmaceutical compounds. Its ability to be selectively deprotected and incorporated into complex molecules makes it a valuable tool in the development of new drugs.
Used in Chemical Research:
S-Cbz-L-cysteine is utilized in chemical research to study the properties and reactions of protected amino acids. Its unique reactivity and solubility characteristics make it an important subject of investigation in the field of chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 1625-72-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,2 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1625-72:
(6*1)+(5*6)+(4*2)+(3*5)+(2*7)+(1*2)=75
75 % 10 = 5
So 1625-72-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO4S/c12-9(10(13)14)7-17-11(15)16-6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)

1625-72-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-2-Amino-3-(((benzyloxy)carbonyl)thio)propanoic acid

1.2 Other means of identification

Product number -
Other names S-Cbz-L-cysteine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1625-72-5 SDS

1625-72-5Relevant articles and documents

S-NITROSOTHIOL COMPOUNDS AND RELATED DERIVATIVES

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Page/Page column 52, (2008/12/06)

The present invention is directed to a method of treating a lack of normal breathing control including the treatment of apnea and hypoventilation associated with sleep, obesity, certain medicines and other medical conditions. In an aspect, the invention is directed to treating disordered control of breathing by administering an composition comprising a single compound which treats lack of normal breathing. In another aspect, the invention is directed to treating disordered control of breathing by administering an composition comprising a combination of two or more compounds, at least one of which treats lack of normal breathing. In an aspect, a compound is an S-nitrosylating agent.

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