16948-09-7Relevant articles and documents
HIV protease inhibitors based on amino acid derivatives
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, (2008/06/13)
A compound selected from the group consisting of a compound of formula I 1a compound of formula II 2and when the compound of formula I and II comprises an amino group pharmaceutically acceptable ammonium salts thereof, wherein R1, R2, Cx, n, R3, R4, R5, Y are as defined in the specification.
The novel synthesis of the protease inhibitor (S)-1-chloro-3-[(p-tolylsulfonyl)amino]-7-amino-2-[5,5,6,6-3H]heptanone ([3H]T:CK labeled to high specific activity with tritium
Villani,Heys
, p. 379 - 386 (2007/10/03)
The protease inhibitor (S)-1-chloro-3-[(p-tolylsulfonyl)amino][5,5,6,6-3H] heptanone (3H3TLCK) was prepared in an overall 41% radiochemical yield with a specific activity of 1.6 Ci/mmol in a 'one-pot' 3 step sequence begin